Grundlage und Aussichten eines neuen röntgentherapeutischen Verfahrens: Homogenisierung der Röntgenstrahlen mittels eines Gewebsäquivalentfilters

Groedel, Franz M.

doi:10.1055/s-0028-1140346

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2018

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“…However, the technique was never adopted in a clinical setting because the donor vessels were inadequate. Subsequently, Wrede used veins as nerve conduits for the first time in 1909 (Wrede, ). Sufficient regrowth of axons will be feasible in a 3 cm long vein nerve conduit (Strauch et al, , ), in longer conduits (3.5–5 cm) regrowth is uncommon and in conduits with gaps measuring 6 cm, nerve regeneration is at no time observed.…”

Section: Introductionmentioning

confidence: 99%

Nerve repair and regeneration: Biological tubulization limits and future perspectives

Riccio¹,

Marchesini²,

Pugliese³

et al. 2018

Journal Cellular Physiology

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Peripheral nerve physiology and regeneration has been observed and investigated in literature but surgical applications to reconstruct and restore motor or sensory functions are still in a developmental phase. The peripheral nerve progresses slowly and incompletely compared with other tissues, it may provoke separations of the nerve stumps and the axonal proliferation of the conduits is restricted to 30 mm. Recent surgical attempts to treat proximal nerve injures include direct nerve restoration, transfer, and autografting measures with favorable results. Moreover, studies are suggesting that engineering tissue tubes maybe as effective as nerve grafting to restore separations of more than 4 cm toward optimal nerve repair.

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Section: Introductionmentioning

confidence: 99%