Artemisia annua L. is an aromatic-antibacterial herb that destroys malarial parasites, lowers fever, and checks bleeding, and from which the secondary compound of interest is artemisinin. It has become increasingly popular as an effective and safe alternative therapy against malaria, and its derivatives are effective against multidrug resistant Plasmodium falciparum strains. Nitrogen is required by the plants in the largest quantity and is most limiting where biomass production is desired. On the other hand, gibberellic acid plays an important role in flowering, growth, and development and also in other physiological and biochemical processes. The feasibility of foliar GA 3 (75 mg$L -1 ) alone or with varying levels of soil applied nitrogen (40, 80, and 120 mg$kg -1 soil) was tested on A. annua in the present study. The application of GA 3 proved effective in alleviating the growth, photosynthesis, and enzyme activities of A. annua. However, N levels combined with GA 3 showed better responses, and further improvement in these parameters was observed. Furthermore, the most important task we were interested in was to increase the artemisinin content and its yield on a per plant basis. The N combination (80 mg$kg -1 soil) together with GA 3 augmented the content (21.8% more) and yield (55.8% more); this is true for both the treated plants, which were more than the control.