Growth performance, biochemical and haematological parameters of BALB/c mice fed on staple grains and bee larvae (Apis Mellifera) blended complementary foods

Mekuria, Shewangzaw Addisu; Kinyuru, John; Mokua, Beatrice Kiage; Tenagashaw, Mesfin Wogayehu

doi:10.1016/j.heliyon.2022.e09003

Cited by 4 publications

(2 citation statements)

References 69 publications

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“…Table 1 shows the nutritional composition of the developed and commercial complementary diets. Te proximate analysis of experimental diets and commercial wean mix data (Table 1) that used to support the fndings of this study were published previously [27].…”

Section: Diet Formulation and Preparationmentioning

confidence: 83%

Cardioprotective Effects of Insect Apis melifera‐Based Complementary Foods Using an In Vivo Mouse Model

Mekuria

Mokua

Tenagashaw

et al. 2023

Evidence-Based Complementary and Alternative Medicine

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Background. Cardiovascular disease is the cause of one-third of deaths worldwide because of increased risk factors, such as intake of cholesterol and saturated fat. Atherosclerosis begins in childhood; therefore, nutritional prevention should begin at an early stage. This study assessed the lipid profile, atherogenic, and castill’s risk index intake of Apis melifera-based complementary foods using an in vivo mouse model. Methods. The experiment was conducted for 28 days. A total of 75 male white albino mice were randomly assigned to five diets in triplicate. The diets were Diet 1 = casein diet; Diet 2 = (57% maize, 29% teff, 14% soybean); Diet 3 = (58% maize, 29% teff, 13% bee larvae); Diet 4 = commercial wean mix; Diet 5 = basal diet alone. Mouse blood samples were collected by cardiac puncture. The lipid profiles of TC, TG, HDL-C, and LDL-C were analysed using an automated pentra C400 made in France. Results. Biochemical (mg/dl) parameters showed that mice fed Diet 3 had high ( P ≤ 0.001), TG (167.79), HDL-C (67.18), and low LDL-C (71.73) levels. The atherogenic indices CRI-I (1.84), CRI-II (1.07), and AC (0.84) were low in Diet 3. The atherogenicity indices showed a significant positive correlation ( P ≤ 0.001) with one another as follows: CRI-I vs. CRI-II (r = 0.919), CRI-I vs. AC (r = 1), and CRI-II vs. AC (r = 0.919). Conclusion. The results of the present investigation confirm that intake of an Apis mellifera-based diet could prevent children from atherosclerotic cardiovascular disease in a mouse model.

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Section: Diet Formulation and Preparationmentioning

confidence: 83%

Cardioprotective Effects of Insect Apis melifera‐Based Complementary Foods Using an In Vivo Mouse Model

Mekuria

Mokua

Tenagashaw

et al. 2023

Evidence-Based Complementary and Alternative Medicine

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“…[16,17] Its primary function is to transport oxygen to various tissues and organs in the body. [18] Low Hb levels in elderly individuals are frequently associated with factors such as advanced age, trauma, underlying diseases, and malnutrition. According to previous research, [19][20][21][22] preoperative anemia affects between 15.3% to 55.4% of patients with hip fractures.…”

Section: The Authors Have No Conflicts Of Interest To Disclosementioning

confidence: 99%

Relationship between preoperative hemoglobin levels and length of stay in elderly patients with hip fractures: A retrospective cohort study

Zhang,

Ren

et al. 2024

Medicine

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Globally, hip fractures in elderly individuals are a prevalent and serious issue. Patients typically have a longer length of stay (LOS), which increases the risk of complications and increases hospitalization costs. Hemoglobin (Hb) is a routine blood test that is associated with disease prognosis. This study aimed to investigate the relationship between preoperative Hb and LOS in elderly hip fracture patients and to determine a reliable transfusion threshold. The clinical data of hip fracture patients (aged ≥ 60 years) admitted to the Department of Orthopaedics, Shenzhen Second People’s Hospital, between January 2012 and December 2021 were retrospectively analyzed. Multiple linear regression analysis was used to assess the linear relationship between preoperative Hb and LOS. Smooth curve fitting was performed to investigate potential nonlinear relationships. In the case of discovering nonlinear relationships, a weighted two-piecewise linear regression model was built, and the inflection points were determined using a recursive algorithm. Subgroup analyses were conducted based on age and gender. A total of 1444 patients with an average age of (77.54 ± 8.73) years were enrolled. After adjusting for covariates, a nonlinear relationship was found between preoperative Hb and LOS. The two-piecewise linear regression model revealed an inflection point of 10 g/dL. On the left of the inflection point (Hb < 10 g/dL), the LOS was reduced by 0.735 days for every 1 g/dL increase in Hb (β = ‐0.735, 95% confidence interval: ‐1.346 to ‐0.124, P = .019). On the right side of the inflection point (Hb > 10 g/dL), the relationship was not statistically significant (β = 0.001, 95% confidence interval: ‐0.293 to 0.296, P = .992). In elderly hip fracture patients, there is a nonlinear association between preoperative Hb and LOS. However, when Hb levels were <10 g/dL, there was a negative correlation with the LOS. No correlation was observed when Hb levels were >10 g/dL. These findings underscore the importance of timely intervention to manage Hb levels in elderly patients with hip fractures, potentially reducing hospitalization durations and associated complications.

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Dietary Supplementation with Apis mellifera Wholemeal Flour Reduces Hepatic Steatosis in Obese Mice

Nascimento,

Pereira,

Caldas

et al. 2024

Journal of Medicinal Food

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Growth performance, biochemical and haematological parameters of BALB/c mice fed on staple grains and bee larvae (Apis Mellifera) blended complementary foods

Cited by 4 publications

References 69 publications

Cardioprotective Effects of Insect Apis melifera‐Based Complementary Foods Using an In Vivo Mouse Model

Cardioprotective Effects of Insect Apis melifera‐Based Complementary Foods Using an In Vivo Mouse Model

Relationship between preoperative hemoglobin levels and length of stay in elderly patients with hip fractures: A retrospective cohort study

Dietary Supplementation with Apis mellifera Wholemeal Flour Reduces Hepatic Steatosis in Obese Mice

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