Growth Performance and Serum Lipids Profile of <i>Clarias gariepinus</i> Catfish Following Experimental Dietary Exposure to Fumonisin B<sub>1</sub>

Abstract

Fumonisin B 1 (FB 1) is produced by fungus of the genus Fusarium (Fusarium verticiloides and F. proliferatum), and occurs predominantly in maize. The consumption of feed contaminated with FB 1 has been reported to cause deleterious effects in some fish species. This study was designed to determine the effects of dietary FB 1 on growth and lipids profile of Clarias gariepinus. 450 juvenile catfish were stocked into 5 groups of tanks consisting of 3 tanks per group and fed one of five diets amended with FB 1 (0.0 mg; 10.0 mg; 20.0 mg; 40.0 mg and 80.0 mg FB 1 /kg) for 56 days. At time point's day 7, 14, 28 and 56, five fish were sampled from each tank weighted, length measured and bled for of lipids profile determinations. Results show that there was a significant reduction (P < 0.05), in the mean body length of the fish fed diets amended with various amounts of FB 1 compared with those fed control diet; also, there was a significant reduction (P < 0.05) in the weight gain of fishes fed diets amended with FB 1 compared with the control. The specific growth rate and the feed conversion ratio at 56 days shows fish fed 0.0 mg FB 1 /kg had the highest specific growth rate (0.39 ± 0.14%/day) and the lowest feed conversion ratio (0.59 ± 0.01) whereas, fish fed 80.0 mg FB 1 /kg had the least specific growth rate (0.07% ± 0.01%/day) and the highest feed conversion ratio (1.95 ± 0.11). Dietary FB 1 caused significant increases (P < 0.05) in serum cholesterol, HDL-C; LDL-C; triglycerides and the sphinganine-sphingosine ratio. Dietary FB 1 at an inclusion rate ≥ 20 mg FB 1 /kg of diet produced significant reduction in weight gain and hyperlipidemia * Corresponding author. B. T. Adeyemo et al. 128 marked by hypercholesterolemia, increased blood high-density lipid cholesterol, increased blood low-density lipid cholesterol, elevated blood triglycerides and elevated sphinganine-sphingosine ratio.

Serum Biochemistry Reference Intervals of <i>Clarias gariepinus</i> Farmed in Earthen Pond Systems in the Southern Guinea Savanna Agro-Ecological Zone of Nigeria

“…The changes in some serum biochemical indices of farmed Clarias gariepinus caused by stress due to exposure to environmental pollutants, pathogen challenge, or nutritional toxicities have been reported (Onusiruke and Ufodike, 2000;Oladele et al, 2011;Adeyemo et al, 2016). According to Lio-po and Lim (2002) more data is needed for monitoring of managements and or therapeutic interventions in the culture of this fish species.…”