Growth failure and sleep disordered breathing: A review of the literature

Bonuck, Karen; Parikh, Sanjay R.; Bassila, Maha

doi:10.1016/j.ijporl.2005.11.012

Cited by 128 publications

(90 citation statements)

References 62 publications

(101 reference statements)

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“…Growth failure has been frequently reported (27%-56%) in children who have obstructive sleep apnea syndrome (OSAS). [1][2][3][4][5] Adenotonsillar hypertrophy is the primary cause of OSAS in children, and is usually treated with adenotonsillectomy (AT). AT has been reported to accelerate weight [6][7][8][9][10][11][12][13][14] in children with baseline failure to thrive (FTT), 1,3,4,15 normal weight patients, 9,11,14,[16][17][18][19][20] obese individuals, 9,13,16,21,22 and infants.…”

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confidence: 99%

Growth After Adenotonsillectomy for Obstructive Sleep Apnea: An RCT

et al. 2014

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BACKGROUND AND OBJECTIVES: Adenotonsillectomy for obstructive sleep apnea syndrome (OSAS) may lead to weight gain, which can have deleterious health effects when leading to obesity. However, previous data have been from nonrandomized uncontrolled studies, limiting inferences. This study examined the anthropometric changes over a 7-month interval in a randomized controlled trial of adenotonsillectomy for OSAS, the Childhood Adenotonsillectomy Trial. METHODS: A total of 464 children who had OSAS (average apnea/hypopnea index [AHI] 5.1/hour), aged 5 to 9.9 years, were randomized to Early Adenotonsillectomy (eAT) or Watchful Waiting and Supportive Care (WWSC). Polysomnography and anthropometry were performed at baseline and 7-month follow-up. Multivariable regression modeling was used to predict the change in weight and growth indices. RESULTS: Interval increases in the BMI z score (0.13 vs 0.31) was observed in both the WWSC and eAT intervention arms, respectively, but were greater with eAT (P < .0001). Statistical modeling showed that BMI z score increased significantly more in association with eAT after considering the influences of baseline weight and AHI. A greater proportion of overweight children randomized to eAT compared with WWSC developed obesity over the 7-month interval (52% vs 21%; P < .05). Race, gender, and follow-up AHI were not significantly associated with BMI z score change. CONCLUSIONS: eAT for OSAS in children results in clinically significant greater than expected weight gain, even in children overweight at baseline. The increase in adiposity in overweight children places them at further risk for OSAS and the adverse consequences of obesity. Monitoring weight, nutritional counseling, and encouragement of physical activity should be considered after eAT for OSAS.

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Section: (Continued On Last Page)mentioning

confidence: 99%

Growth After Adenotonsillectomy for Obstructive Sleep Apnea: An RCT

et al. 2014

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“…Other disorders have also been described in association with obstructive apnea: enuresis, 10 night sweats, daytime sleepiness, behavior disorders, d e v e l o p m e n t a l d e l a y ( r e l a t e d t o h e i g h t and weight growth and learning), 11 arterial hypertension 12 and, in extreme cases, pulmonary hypertension and right heart failure. 13 Although it is a common sign, it is not normal for a child to snore.…”

Section: Discussionmentioning

confidence: 99%

Assessment of quality of life before and after an adenotonsillectomy among children with hypertrophic tonsils and/or adenoids

2015

Arch Argent Pediat

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Introduction.Adenotonsillectomy is the most common surgical procedure in otolaryngology. The main indication for this procedure is upper airway obstruction associated with hypertrophic tonsils and/or adenoids. Objectives. To describe the differences in quality of life before and after an adenoidectomy and/ or tonsillectomy and compare it with that of healthy children. Population and Methods. All children aged 1 to 17 years old hospitalized for an elective surgery between July 2012 and April 2014 were enrolled. They were compared to a control group of children in the same age range. The survey used was validated in Spanish (OSA-18) and has been especially designed to establish a relationship between obstructive sleep apnea and quality of life in pediatrics. Results. Eighty-five surgery patients and 100 healthy control children were assessed. The impact on quality of life was mild in 37.6% of children, moderate in 32.9%, and severe in 29.4%, while it was mild for 96% of the control group. The average ± SD of the total pre-surgery score was 67.5 ± 20.3 (95% confidence interval [CI]: 63.13-71.88). The average post-surgery scores were 37.9 ± 21.4 (95% CI: 33.24-42.48) and ) at 3 and 6 months, respectively (p < 0.001). The average score for the control group was 31.2 ± 13.2 (95% CI: 28.6-33.8) and was significantly different from the post-surgery groups (p = 0.03). Conclusions. Quality of life was reduced in children with a surgical indication for symptomatic adenotonsillar hypertrophy, while it was significantly improved after the surgery.

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“…También se han descrito otras alteraciones asociadas a la presencia de apneas obstructivas: enuresis, 10 sudoración nocturna, somnolencia diurna, alteraciones conductuales, retraso del desarrollo (pondoestatural y del aprendizaje), 11 hipertensión arterial 12 y, en grados extremos, hipertensión pulmonar e insuficiencia cardíaca derecha. 13 A pesar de ser un signo frecuente, no es normal que un niño ronque.…”

Section: Discussionunclassified

Evaluación de la calidad de vida antes y después de la adenotonsilectomía en niños con hipertrofia de amígdalas y/o adenoides

2015

Arch Argent Pediat

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Growth failure and sleep disordered breathing: A review of the literature

Cited by 128 publications

References 62 publications

Growth After Adenotonsillectomy for Obstructive Sleep Apnea: An RCT

Growth After Adenotonsillectomy for Obstructive Sleep Apnea: An RCT

Assessment of quality of life before and after an adenotonsillectomy among children with hypertrophic tonsils and/or adenoids

Evaluación de la calidad de vida antes y después de la adenotonsilectomía en niños con hipertrofia de amígdalas y/o adenoides

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