“…The nonlinear optical properties of the different chalcone derivatives have also been reported. [5][6][7][8] These α, β-unsaturated ketones possess a wide variety of biological activities, including anti-leishmanial 9 , anti-invasive 10 , antituberculosis 11 , anti-fungal 12 , anti-malarial. 13,14 The crystal structures of some dimerized chalcones such as r-1,c-2,t-3,t-4-1,3-bis(4-methoxyphenyl)-2,4-bis(5-phenyl-1,3,4-oxadiazol-2-yl)cyclobutane 1,4-dioxane solvate 15 and r-1,c-2,t-3,t-4-1,2-bis(4-methoxyphenyl)-3,4-bis(5-phenyl-1,3,4-oxadiazol-2-yl) cyclobutane 16 exist in the literature.…”