Growth and morphology of ultra-thin Al films on liquid substrates studied by atomic force microscopy

Zheng-Nong, Fang; Yang, Bo; Chen, Miaogen; Zhang, Chuhang; Xie, Jianping; Ye, Gao-Xiang

doi:10.1016/j.tsf.2009.01.017

Cited by 18 publications

(16 citation statements)

References 24 publications

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“…Figure b displays the log–log plots of 1DPSD spectra as a function of the frequency f . Clearly, a characteristic plateau in low frequency region (indicated by the horizontal dash line) can be found in each spectrum, suggesting the absence of nonlocal correlations along the line scans, while the steeper portion in high frequency region (the sloping dash line) is taken as the self‐affine range . The intensity corresponding to the low frequency plateaus, depicting the effect of flux noise on growing surfaces, is increased with the deposition time except for the 5 and 10 min cases.…”

Section: Resultsmentioning

confidence: 94%

On‐Demand Preparation of α‐Phase‐Dominated Tungsten Films for Highly Qualified Thermal Reflectors

Wang

Zang

Gao

et al. 2019

Adv Materials Inter

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Phase‐structure diversity affords tungsten thin films with fascinating physical/chemical properties for varied applications. However, the on‐demand preparation of W films with specific phase is still an important but unmet scientific issue. In this report, an easy‐to‐achieve preparation recipe is implemented for addressing the phase tailoring of tungsten films. The phase transformation evolution during deposition is governed by enhanced diffusion of W adatoms and selective atomic etching on the crystal planes. It is experimentally demonstrated that the orientation relation between {210}β and {110}α planes plays a vital role in coupling with the competitive growth behaviors between β‐ and α‐W. The phase‐dependent electrical/optical properties of W films are experimentally observed and unambiguously figured out by theoretical simulations. Alpha‐phase‐dominated W films are prepared successfully under relatively tolerant conditions, demonstrating a low resistivity of ≈13.6 µΩ cm and a high infrared reflectance larger than 93%. Alpha‐W also serves as thermal reflector to construct a solar absorber, exhibiting a low thermal emissivity of ≈9.8%@500 °C. Understanding the (α, β) phase transformation mechanism means a big step forward in the development of the on‐demand preparation, which allows to build a scalable platform for making W films with specific phase in a more controllable way.

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Section: Resultsmentioning

confidence: 94%

On‐Demand Preparation of α‐Phase‐Dominated Tungsten Films for Highly Qualified Thermal Reflectors

Wang

Zang

Gao

et al. 2019

Adv Materials Inter

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“…The roughness exponent was obtained by analyzing the one dimensional power spectra density (1DPSDs) of the film surfaces. 19) In one dimensional case, the 1DPSD can be defined as the Fourier expansion of spatial frequency f s : 1=l Ã ð R hðxÞe i2f s x dxÞ, where l and x represent the scan length and fast scan direction of an area scan, respectively. hðxÞ is the line profile height which can be obtained from the line section of the AFM images.…”

Section: Experimental Methodsmentioning

confidence: 99%

“…hðxÞ is the line profile height which can be obtained from the line section of the AFM images. Since the 1DPSD of the affine structure obeys K 0 f À s , 19) the value is the slope of the linear fit of the double logarithmic diagram of 1DPSD vs f s . In our experiment, the line scan dimension was 1, and then ¼ ð À 1Þ=2.…”

Section: Experimental Methodsmentioning

confidence: 99%

“…[12][13][14][15][16][17][18] A special finding among them is that the Nickel thin films (islands) deposited on the liquid substrates show self-affinity structure and approximately obey the traditional KPZ equation, which allows us to study other metallic island or thin film systems on the liquid surface by employing dynamic scaling analysis. 19) In this paper, we change the nominal film thickness and then a quantitative insight to the growth mechanism of Ag islands deposited on the silicone oil surface is presented. By investigating the scaling exponent, it is found that relationship between the average roughness of the islands and the nominal thickness fits the power-law relationship for the early deposition stage and then deviates obviously from the power-law relationship as the thickness further increases.…”

Section: Introductionmentioning

confidence: 99%

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Anomalous Kinetic Roughening of Nanostructured Ag Islands on Liquid Surfaces

Zhang

Zhu

et al. 2012

J. Phys. Soc. Jpn.

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By atomic force microscopy, the surface evolution and kinetic roughening of nanostructured Ag islands on silicone oil surfaces are studied. It is found that the islands are composed of quasi-circular granules with planar size around 50.0 nm, which is approximately independent of nominal thickness d. Our measurement indicates that the geometrical shape of the granules changes from plateau to sphere as d goes up. The dynamic scaling analysis reveal that the roughness exponent varies between 0.80 and 0.90 as d increases. The average roughness w rms shows power-law relationship with d and the growth exponent ¼ 0:53 AE 0:03 when d 4:0 nm. However, w rms deviates obviously from the power-law relationship for the samples with d > 4:0 nm. This anomalous behavior of is explained by the competition between the shadowing and reemission processes, and then the kinetic evolution and formation mechanism of the islands are presented.

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“…Vascular targeting agents (VTAs) comprise a novel class of anticancer agents which can be divided into two groups; those that inhibit angiogenesis (angiogenesis inhibitors) and those that target established vessels (vascular disrupting agents) (17). Various combinations involving an antiangiogenic agent and an antivascular agent have shown considerable promise in preclinical models and such combinations are currently beginning to be evaluated in patients (18,19). Thus, we hypothesized that combining the antiangiogenic drug dasatinib with the antivascular agent CA-4 might potentially enhance the anticancer therapeutic effects.…”

Section: Introductionmentioning

confidence: 99%

Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo

Zhang

Zhou

et al. 2013

Oncology Reports

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Abstract. The present study showed that the combination of dasatinib and combretastatin A-4 (CA-4) exhibited synergistic cytotoxicity in multiple types of cancer, including ovarian, hepatocellular, lung and prostate carcinoma. The enhanced apoptosis induced by dasatinib plus CA-4 was accompanied by a greater extent of mitochondrial depolarization, caspase-3 activation and PARP cleavage in HO-8910 cells. Furthermore, elevated expression of Mcl-1 led to a reduced apoptosis induced by dasatinib plus CA-4, highlighting that downregulated Mcl-1 was necessary for the potentiating effect of dasatinib to CA-4-triggered apoptosis. A clear increase in γ-H2AX expression was observed in the dasatinib + CA-4 group compared with the mono-treatment groups, indicating that dasatinib plus CA-4 may induce double-strand breaks (DSBs) in HO-8910 cells. Moreover, the increased anticancer efficacy of dasatinib combined with CA-4 was further validated in a human HO-8910 ovarian cancer xenograft model in nude mice. Our study is the first to show that the combination of dasatinib with CA-4 could be a novel and promising therapeutic approach for the treatment of cancer. IntroductionCombretastatin A-4 (CA-4), a natural product isolated from the bark of a south african tree combretum caffrum, is a highly effective antiangiogenic agent that causes vascular shutdown, leading to tumor death (1). CA-4 phosphate (CA-4P), a water soluble pro-drug of CA-4, is rapidly dephosphorylated to the active compound CA-4 and shows reversible binding kinetics to tubulin, leading to disruption of microtubular structures (2,3). Although CA-4P is being studied in clinical trials as a vascular disrupting agent, cardiovascular toxicity and neurotoxicity are dose limiting for CA-4P (4,5). These severe side-effects currently represent the main obstacles to broad clinical application of CA-4P (2). Thus, it is important to develop new antitumor combination therapy with lower concentrations of CA-4 and more specificity for tumor endothelial cells than normal endothelial cells to avoid cardiac toxicity from endothelial damage.Tyrosine kinase inhibitors (TKIs) are rapidly being integrated into the management of a variety of malignant diseases (6). Dasatinib, a novel orally bioactive TKI currently used to treat patients with hematologic and solid malignancies, correlated with a combined targeting of PDGFR-β and VEGFR/c-Src signaling pathways (7-9). The Src kinases have multiple substrates that lead to diverse biological effects in cancer cells, including changes in proliferation, motility, invasion, survival and angiogenesis (10). Dasatinib suppresses tumor angiogenesis, invasion, and metastasis by inhibiting Src expression (11). Cardiovascular and hematologic toxicity are dose limiting for dasatinib; thus, it is necessary to develop new anticancer combination therapy with lower concentrations of dasatinib to avoid these major side-effects (12). Dasatinib has shown synergistic anticancer activity in combination with chemotherapeutic agents including paclitaxel, ixabepil...

show abstract

Growth and morphology of ultra-thin Al films on liquid substrates studied by atomic force microscopy

Cited by 18 publications

References 24 publications

On‐Demand Preparation of α‐Phase‐Dominated Tungsten Films for Highly Qualified Thermal Reflectors

On‐Demand Preparation of α‐Phase‐Dominated Tungsten Films for Highly Qualified Thermal Reflectors

Anomalous Kinetic Roughening of Nanostructured Ag Islands on Liquid Surfaces

Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo

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