Abstract:Klinefelter syndrome (KS) is the most common chromosomal aberration in men. The prevalence of KS in male reproductive practices is 3-4%; however, most children and adolescents are either never diagnosed or are diagnosed late because of infertility in adulthood. KS has an effect on normal development, growth, social interactions, bone structure, and sexual and reproductive function. The aim of this chapter is to review critical aspects of growth and development in children and adolescents with KS (47,XXY) based… Show more
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