Grover's disease in chronic kidney failure

Rodríguez-Pazos, L.; Vilas‐Sueiro, Alejandro; González‐Vilas, D.; Durana, C.

doi:10.1016/j.nefroe.2015.06.009

Cited by 5 publications

(4 citation statements)

References 7 publications

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“…This resulted in the rejection of 104 articles. All articles were screened according to the scheme presented in Figure , . A total of 116 original reports met the inclusion criteria and were analyzed, including 88 case reports, 26 case series and two retrospective reviews .…”

Section: Resultsmentioning

confidence: 99%

Clinical features and treatments of transient acantholytic dermatosis (Grover’s disease): a systematic review

Bellinato

Maurelli

Gisondi

et al. 2020

J Deutsche Derma Gesell

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Summary Grover's disease (GD) is an itchy acantholytic disorder occurring on the trunk of middle‐aged men. Based on the best evidence, this study aimed to provide a summary of the clinical characteristics, disease course and treatments of GD. A systematic review was performed according to PRISMA guidelines for original articles published between 01.01.1970–08.15.2019, assessing clinical features and/or any type of intervention for GD. A total of 263 articles were retrieved, and 116 original reports that were deemed relevant and satisfied the inclusion criteria were included in the analysis (88 case reports, 26 case series and two retrospective reviews). From these articles, 317 patients were identified, with a male‐to‐female ratio of 3.95. The mean age was 59 years (range 11–92). Typical lesions were itchy papules and vesicle‐papules, generally located on the trunk. Spontaneous resolution within one week to eight months was described in 42 % of cases. Topical corticosteroids (TCSs) were the most frequent treatment (response rate of 70 %) followed by systemic retinoids and corticosteroids with response rates of 86 % and 64 %, respectively. According to the results of this review, TCS appears to be the most frequently employed treatment, and we suggest TCS as first‐line therapy. Second‐line treatments could include systemic retinoids or systemic corticosteroids.

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Section: Resultsmentioning

confidence: 99%

Clinical features and treatments of transient acantholytic dermatosis (Grover’s disease): a systematic review

Bellinato

Maurelli

Gisondi

et al. 2020

J Deutsche Derma Gesell

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“…1 Fever or prolonged bed rest, sweating or excessive heat, exposure to UV radiation, treatment with ionizing radiations, xerosis and some drugs have been associated with this disease. 3 This affection is due to sweat ducts obstruction and from the leakage of products that induce acantholysis. However, the possibility still exists that smaller molecules may seep through the ductal epithelium and cause epidermal acantholysis.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2021

JDC

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Grover's diseaseis an itchy acantholytic disorder occurring on the trunk of middle-aged men. It is a transient dermatosis of unknown cause manifesting clinically as a papular skin eruption located usually on the anterior chest and abdomen and histologically with dyskeratosis and acantholysis. This disease has occasionally been reported in patients with chronic renal failure, some infections, hematological malignancies, and many other anomalies. We report herein a new case of Grover's disease that developed in a female patient after a fever episode.

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“…Various medical conditions have been associated with GD eruptions. To date, there are 14 published cases of GD in chronic renal failure, of which most occurred after initiating hemodialysis . Malignancy is also common in these patients, especially those with extensive disease, and GD is often found following induction of chemotherapy .…”

Section: Review Of Etiopathogenesis Of Grover Diseasementioning

confidence: 99%

Grover disease: review of subtypes with a focus on management options

Aldana

Khachemoune

2019

Int J Dermatology

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Grover disease (GD) is a benign eruption that causes a papulovesicular rash on the trunk and proximal extremities. It often resolves spontaneously but can follow a more chronic and fluctuating course that may last several years. Although the etiology remains unknown, several associated triggers have been identified including heat and sweating, cool and dry air, renal failure, malignancy, and the initiation of several drugs. Since the disease tends to resolve on its own, management is aimed at disease prevention and symptomatic relief. First-line therapy includes topical steroids and vitamin D analogues with adjuvant antihistamines. In more severe cases that are refractory to less aggressive therapy, systemic corticosteroids, retinoids, and phototherapy may lead to successful resolution. Novel therapies are few and have little evidence but involve innovative use of light therapy and immune modulators. Herein, we review the literature and new trends of GD with a focus on established and novel treatments. Historical evolution of our understanding of Grover disease Grover disease was first described in 1970 as a self-limited eruption of pruritic, discrete, and edematous papules and vesicles which appeared on the trunk and extremities following nonspecific irritation. These lesions occurred in six patients without family history of skin disease and had a duration of a few weeks up to several months. Cytology of the lesions revealed focal acantholysis within the epidermis and varying levels of dyskeratosis that resembled changes seen in Darier and Hailey-Hailey ª

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Grover's disease in chronic kidney failure

Cited by 5 publications

References 7 publications

Clinical features and treatments of transient acantholytic dermatosis (Grover’s disease): a systematic review

Clinical features and treatments of transient acantholytic dermatosis (Grover’s disease): a systematic review

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Grover disease: review of subtypes with a focus on management options

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