Group B Streptococcus Colonization in Pregnancy: Prevalence, Determinants and Antibacterial Susceptibility Pattern in Sagamu, Nigeria

Akadri, Adebayo; Osuolale, Bamidele D.; Shorunmu, T.O.; Odelola, Oluwaseyi Isaiah

doi:10.9734/jammr/2019/v29i1030131

Cited by 3 publications

(9 citation statements)

References 17 publications

(30 reference statements)

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“…[ 15 ] who reported the highest prevalence rate between 31 and 35 years and Akadri et al . [ 5 ] whose study recorded the highest prevalence in women above 30 years of age, although there was no significant association between age and GBS colonisation.…”

Section: Discussionmentioning

confidence: 95%

“…The prevalence recorded in this current study was lower than that reported in China, Ethiopia, South Africa, and in various regions in Nigeria. [ 2 3 4 5 6 13 14 15 ] A wide range of prevalence rates of 8.6–34.2% have been reported in different studies worldwide. [ 2 3 4 5 6 13 14 15 ] These differences including the one observed in our study probably may be due to the different environments and populations in which the various studies were carried out.…”

Section: Discussionmentioning

confidence: 99%

“…[ 2 3 4 5 6 13 14 15 ] A wide range of prevalence rates of 8.6–34.2% have been reported in different studies worldwide. [ 2 3 4 5 6 13 14 15 ] These differences including the one observed in our study probably may be due to the different environments and populations in which the various studies were carried out. The difference in the prevalence may also be due to the different means of inoculation/culture.…”

Section: Discussionmentioning

confidence: 99%

“…[ 2 ] while a prevalence of 8.6–64% GBS colonisation of mothers and 19.0–20.6% among newborns were reported in Nigeria depending on the methods of isolation of the organism. [ 3 4 5 6 ]…”

Section: Introductionmentioning

confidence: 99%

“…Several studies have been carried out in Nigeria, including Southwest Nigeria, in which GBS colonisation was studied in late pregnancy and a wide range of prevalences has been reported. [ 3 5 6 ] Despite the numerous studies, no clear-cut guidelines on screening or management have been developed in Nigeria and presently many centres in Nigeria do not screen for GBS in pregnant women or their newborns, either universally or based on risk. More evidence-based reports may help in designing a guideline and developing recommendations.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of group B Streptococcus colonisation and antimicrobial susceptibility pattern among pregnant women attending a tertiary health facility in Ogun State, Southwest Nigeria

Adenaya¹,

Ojo²,

Awonuga³

et al. 2019

J West Afr Coll Surg

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Background: Genital colonisation by group B Streptococcus (GBS) in pregnant women in their third trimester has been shown to be a known risk factor for morbidity and mortality among newborns. Aim: The aim of the study was to determine the prevalence of GBS colonisation among pregnant women in Abeokuta, its associated sociodemographic factors, and the neonatal outcome among exposed babies. Design: Longitudinal cohort study. Setting: Department of Obstetrics and Gynaecology, Federal Medical Centre, Abeokuta, Ogun State. Methodology: One hundred sixty pregnant women presenting for routine antenatal care between 35 and 41 weeks were recruited consecutively. Swabs were taken from the vagina and then the rectum using a single swab. The samples were processed at the hospital's Medical Microbiology Laboratory using standard microbiological methods. Babies whose mothers were positive had their bodies swabbed and the samples sent for GBS isolates. They were also screened for early-onset neonatal sepsis with C-reactive protein. Results: Prevalence of GBS vaginal colonisation was 4.3%. There was no significant association between GBS colonisation status and age, level of education, or occupation; however, women of parity ≤1 had significantly higher prevalence of GBS colonisation than those of parity ≥2. There was no incidence of GBS infection observed in the babies. The GBS isolates were 100% sensitive to cefuroxime and 83.3% resistant to ampicillin. Conclusion: The prevalence of GBS is low in our environment. The organisms were highly sensitive to cefuroxime, erythromycin, and ceftriaxone. Routine screening of all pregnant women may be unnecessary. However, women at risk of GBS who present in labour without a recent GBS screening should be offered intrapartum prophylactic cefuroxime.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Prevalence of group B Streptococcus colonisation and antimicrobial susceptibility pattern among pregnant women attending a tertiary health facility in Ogun State, Southwest Nigeria

Adenaya¹,

Ojo²,

Awonuga³

et al. 2019

J West Afr Coll Surg

View full text Add to dashboard Cite

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Prevalence of Group B Streptococcus maternal colonization, serotype distribution, and antimicrobial resistance in Sub-Saharan Africa: A systematic review and meta-analysis

Wadilo¹,

Hailemeskel²,

Kedir³

et al. 2023

Journal of Global Antimicrobial Resistance

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Epidemiology and Capsular Typing of Group B Streptococcus in Pregnant Women in Port Harcourt, Nigeria

Mienyea,

Stephenson D.Kasso Terhemen,

Ibinabo L.

et al. 2021

Ann Microbiol Infect Dis

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Background: Colonization of the lower vagina and anorectum of pregnant women by group B streptococcus (GBS) in the third trimester is a risk factor for early neonatal disease. This study was carried out to determine the prevalence of rectovaginal colonization and capsular type distribution of GBS among pregnant women in Port Harcourt, Nigeria. Methods: Group B streptococci were isolated and identified from vaginal and anorectal swabs using CHROMagar, CAMP test and latex agglutination while capsular typing was done using multiplex PCR. Results: The prevalence of colonization was 18.9%. The capsular polysaccharide types detected by multiplex PCR were Ia, Ib, II, III, IV and V. Capsular types V and Ia were the most frequently occurring among the isolates at 32.6% and 21.7% respectively. While types IV and Ib were the least in frequency (8.7% and 2.2% respectively). A history of urinary tract infection and douching were identified by multiple logistic regression as risk factors for colonization. Conclusion: Lower vaginal and anorectal colonization by group B streptococcus in late pregnancy is significant in this population. The capsular types Ia, Ib, II, III, IV and V, are similar in their occurrence and distribution to other reports from different parts of the world. Nigeria, therefore, would benefit from existing vaccine efforts, targeting the identified capsular types.

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Group B Streptococcus Colonization in Pregnancy: Prevalence, Determinants and Antibacterial Susceptibility Pattern in Sagamu, Nigeria

Cited by 3 publications

References 17 publications

Prevalence of group B Streptococcus colonisation and antimicrobial susceptibility pattern among pregnant women attending a tertiary health facility in Ogun State, Southwest Nigeria

Prevalence of group B Streptococcus colonisation and antimicrobial susceptibility pattern among pregnant women attending a tertiary health facility in Ogun State, Southwest Nigeria

Prevalence of Group B Streptococcus maternal colonization, serotype distribution, and antimicrobial resistance in Sub-Saharan Africa: A systematic review and meta-analysis

Epidemiology and Capsular Typing of Group B Streptococcus in Pregnant Women in Port Harcourt, Nigeria

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