Group B Streptococcal Meningitis Appearing as Acute Deafness in an Adult

Harburg, Thomas D.; Leonard, Hubert A.; Kimbrough, Robert C.; Jones, Stephen R.

doi:10.1001/archneur.1984.04050140116039

Cited by 18 publications

(2 citation statements)

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“…Aqueous penicillin (PCN) was used alone in 11 cases (1,5,6,(10)(11)(12)(13)(16)(17)(18) and in combination with other antibiotics in 5 other cases (4,7,15, this report). The remaining 4 patients were treated with sulfa (2 cases), ampicillin (1 case) or ceftriaxone (1 case) (3,6,12,19).…”

Section: Treatment and Outcomementioning

confidence: 97%

Group B Streptococcal Meningitis in Adults: Case Report and Review of the Literature

Sarmiento

Wilson

Khatib

1993

Scandinavian Journal of Infectious Diseases

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A case of group B streptococcal meningitis in an adult is presented with a review of 42 other cases reported in the English literature since 1940. Their median age was 58 years (72.5% were older than 45 years). Male/female ratio was 0.9:1, with male predominance in patients older than 60 years (76.5%). Predisposing illnesses were common but 13.9% of cases reported had no identifiable risk factor. Encephalopathy and bacteremia were frequent (81.3% and 94.4% respectively) and many patients (30%) had other foci of infection. Gram stain of cerebrospinal fluid was positive in 75% of cases. Mortality was 18.4% and 9.7% of survivors had bilateral hearing loss. Thus, this review illustrates that group B streptococcal meningitis in adults is a rare disease which occurs among high risk individuals. It is characterized by frequent encephalopathy, prevalence of other foci of infection and bacteremia with an outcome similar to other types of purulent meningitides.

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