Group a Beta-Hemolytic Streptococcal Toxic Shock-Like Syndrome

Begovać, Josip; Marton, E; Lisić, Miroslav; Beus, I; D, Bozinović; Kuzmanović, N

doi:10.1097/00006454-199005000-00013

Cited by 43 publications

(9 citation statements)

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“…The association between thoracic empyema due to Streptococcus pyogenes and scarlatiniform rash with acral desquamation has been noted occasionally[8-10], and we suggest that this association may help identify Streptococcus pyogenes as the etiologic agent, particularly when culture results are unavailable. The rash of scarlet fever with subsequent acral desquamation is associated not just with pharyngitis, but may also follow systemic infections with Streptococcus pyogenes in children, including pneumonia[9,11], bacteremia[12,13], septic arthritis[13], Streptococcal toxic shock syndrome[14], and necrotizing fasciitis and cellulitis[11].…”

Section: Discussionmentioning

confidence: 74%

Thoracic empyema with scarlatiniform rash and acral desquamation: a case report

Baird

Sediva

2009

Cases Journal

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Section: Discussionmentioning

confidence: 74%

Thoracic empyema with scarlatiniform rash and acral desquamation: a case report

Baird

Sediva

2009

Cases Journal

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“…In 1987, Cone et al first reported two adult patients with severe GAS infection similar to staphylococcal toxic shock syndrome 1. Paediatric cases of STSS have been reported since 1990 7–9. In 1993, the Working Group on Severe Streptococcal Infection developed a case definition for STSS 10.…”

Section: Discussionmentioning

confidence: 99%

“…Although the overall fatality rate of invasive GAS diseases is lower in children than in adults 5, 6, the case‐fatality rate associated with STSS, reported to be from 47% to 81%, remains high in both paediatric and adult populations 4–6. Skin or mucus membrane is a common portal of entry of streptococci, and previous studies have identified chickenpox as a risk factor for acquiring invasive GAS diseases, including STSS 5–7. To make an early and accurate diagnosis of STSS is a great challenge to physicians, especially in children without skin or soft tissue infections.…”

Section: Introductionmentioning

confidence: 99%

Streptococcal toxic shock syndrome in children without skin and soft tissue infection: Report of four cases

Chiang

Jaing

et al. 2005

Acta Paediatrica

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Streptococcal toxic shock syndrome is a fulminant, highly fatal disease characterized by evidence of group A β‐haemolytic streptococcus infection and early shock with consecutive organ failure. In adults, affected individuals usually have preceding skin or soft tissue infection. However, in paediatric patients, except for varicella, the background focus is usually respiratory tract infection, and early diagnosis of streptococcal toxic shock syndrome in such patients is difficult. We report four previously healthy children with streptococcal toxic shock syndrome. Pharyngitis was identified in three cases. All of them had constitutional symptoms such as fever, vomiting, diarrhoea, abdominal pain and physical findings of tachycardia and diffuse abdominal tenderness, but no concomitant skin infection. Conclusion: Streptococcal toxic shock syndrome should be considered in paediatric patients with fever, vomiting, diarrhoea, abdominal pain and early shock. Early diagnosis, prompt initiation of antibiotics and aggressive fluid therapy are lifesaving for such patients.

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“…Cependant, ces infections invasives restent sporadiques. Les cas groupés s'observent dans un contexte d'infections nosocomiales dans les milieux de chirurgie et 0399 [4,5], ce qui explique la pauvreté en données épidémiologiques concernant la ménin-gite à SGA.…”

Section: Introductionunclassified