Abstract:Group 1 metabotropic glutamate receptors (mGluRs) can positively affect postsynaptic neuronal excitability and epileptogenesis. The objective of the present study was to determine whether group 1 mGluRs might be involved in synaptically-induced intracellular free Ca
2+
concentration ([Ca
2+
]
i
) spikes and neuronal cell death induced by 0.1 mM Mg
2+
and 10 µM glycine in cultured rat hippocampal neurons from embryonic d… Show more
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