A large amount of material in the form of industrial effluents and urban sewage containing metal contaminants directly enters Dudh creek. Metals on entering the creek tend to settle at the bottom and become part of the sediments. The distribution of metals with depth reflects changes in their supply as well as diagenetic modifications with time. In the present study, an attempt has been made to understand the impact of waste discharged from Tarapur Maharashtra Industrial Development Corporation on Dudh creek. Two cores were collected, one close to the creek mouth and the other in the inner part of the creek. Sediment component, organic carbon and metal (vanadium, copper, nickel, lead, zinc, manganese, iron and aluminium) analyses were carried out on the two cores. The variation in the distribution of sediment components with depth reflects changes in hydrodynamic condition of the creek over the years. Increase in concentration of most of the metals in the upper part of the cores indicates additional input in recent years. The core collected in the inner part of the creek showed higher metal and organic carbon concentration as compared to the downstream core. This was very well supported by distribution of points on an isocon plot. Enrichment factor and index of geoaccumulation were used to find the extent of pollution in sediments of the creek. Correlation and R-mode factor analysis have also been computed to understand the association and source of metal input in sediments of Dudh creek.