Groundnut Toxicity in Poultry:

Wannop, C. C.

doi:10.1016/s0007-1935(17)42453-5

Cited by 2 publications

(3 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The disease continued in the same area of London and induced deaths among turkeys on farms as a result of previous feeding with Brazilian groundnut from mills carried by the same company, which included groundnut in the composition of the feed. Groundnut meal was later proved as the main suspect [6,[9][10][11]. Similar liver lesions, considered to be the most serious damage, were found during post mortem examination tests on ducklings, chicken, young pheasants, cattle, rats, and pigs fed with Brazilian groundnut meal [6,9,10,12,13].…”

Section: A History Of Aflatoxin Discoverymentioning

confidence: 91%

“…Groundnut meal was later proved as the main suspect [6,[9][10][11]. Similar liver lesions, considered to be the most serious damage, were found during post mortem examination tests on ducklings, chicken, young pheasants, cattle, rats, and pigs fed with Brazilian groundnut meal [6,9,10,12,13].…”

Section: A History Of Aflatoxin Discoverymentioning

confidence: 91%

“…Mortality varied but was usually high, often with death rates of 50-90% [5]. By the time the disease had subsided, about 500 outbreaks had been reported involving an estimated loss of over 200,000 turkeys [6].…”

Section: A History Of Aflatoxin Discoverymentioning

confidence: 99%

See 2 more Smart Citations

Aflatoxins: History, Significant Milestones, Recent Data on Their Toxicity and Ways to Mitigation

Pickova

Ostrý

Toman

et al. 2021

Toxins

View full text Add to dashboard Cite

In the early 1960s the discovery of aflatoxins began when a total of 100,000 turkey poults died by hitherto unknown turkey “X” disease in England. The disease was associated with Brazilian groundnut meal affected by Aspergillus flavus. The toxin was named Aspergillus flavus toxin—aflatoxin. From the point of view of agriculture, aflatoxins show the utmost importance. Until now, a total of 20 aflatoxins have been described, with B1, B2, G1, and G2 aflatoxins being the most significant. Contamination by aflatoxins is a global health problem. Aflatoxins pose acutely toxic, teratogenic, immunosuppressive, carcinogenic, and teratogenic effects. Besides food insecurity and human health, aflatoxins affect humanity at different levels, such as social, economical, and political. Great emphasis is placed on aflatoxin mitigation using biocontrol methods. Thus, this review is focused on aflatoxins in terms of historical development, the principal milestones of aflatoxin research, and recent data on their toxicity and different ways of mitigation.

show abstract

Section: A History Of Aflatoxin Discoverymentioning

confidence: 91%

Section: A History Of Aflatoxin Discoverymentioning

confidence: 91%

See 1 more Smart Citation

Aflatoxins: History, Significant Milestones, Recent Data on Their Toxicity and Ways to Mitigation

Pickova

Ostrý

Toman

et al. 2021

Toxins

View full text Add to dashboard Cite

show abstract

Licht‐ und elektronenoptische Untersuchungen zur Leberzirrhose nach experimenteller Aflatoxinvergiftung bei Entenküken

Köhler

Schumacher

1967

Zentralblatt für Veterinärmedizin Reihe A

View full text Add to dashboard Cite

Zusammenfassung In zwei Versuchsgruppen (0,03 mg bzw. 0,01 mg jeden 2. Tag, insgesamt 40 Tage) wurde der Einfluß von Aflatoxin auf die Entwicklung einer Leberzirrhose bei Entenküken geprüft. Gegenüber 2 Kontrollgruppen (A Kontroll‐futter, B Versuchsfutter mit Lösungsmittel ohne Aflatoxin) konnte gezeigt werden, daß an den Leberzellen Nekrobiosen und regressive Veränderungen der Mitochondrien sowie verzögerte Eliminierung von Lipiden auftritt. Wesentlich ist die Wucherung von retikulären Fasern, die von mesenchymalen Zellen ausgeht. Die Fasern werden in Nischen der Leberzellen im Disseschen Raum und im dilatierten Interzellularraum zwischen benachbarten Leberzellen gefunden. Neben Gallengangsproliferationen werden die Mesenchymzellproliferationen, Faserbildung und Nekrobiosen als Ausdruck einer Zirrhose gewertet. Summary Histological and electron‐microscopic studies on experimental liver cirrhosis in ducklings produced by aflatoxin The effect of aflatoxin on the development of liver cirrhosis was studied in two groups of ducklings given 0.03 and 0.01 mg. per day, respectively, for 40 days. In comparison with two control groups (one given a control diet and the other the experimental diet with the solvent but no aflatoxin) it was shown that necrobiotic and regressive changes occurred in the mitochondria as well as retarded elimination of lipids. An important feature is proliferation of reticular fibres arising from mesenchymal cells. The fibres are found in niches of liver cells in the space of Disse and in dilated intercellular spaces between the adjacent liver cells. Apart from bile‐duct proliferation, other expressions of cirrhosis included proliferation of mesenchymal cells, new formation of fibres and necrobiosis. Résumé Recherches concernant la cirrhose hépatique suivant l'empoisonnement expérimental par l'aflatoxine chez des canardeaux, effectuées par les méthodes histologiques classiques et au microscope électroniques On étudia dans deux groupes d'essai (0,03 mg resp. 0,01 mg tous les deux jours pendant 40 jours) l'action de l'aflavoxine sur le foie et l'apparition d'une cirrhose hépatique chez les canardeaux. Par rapport à deux groupes de témoins (A, aliment témoin, B, aliment d'essai avec solvant, sans aflatoxine), on put montrer que les cellules hépatiques présentent des nécrobioses et des lésions régressives des mitochondries, ainsi qu'un retard dans l'élimination des lipides. Un fait important est la formation de fibres réticulaires provenant de cellules mésenchymateuses. Ces fibres se trouvent dans des niches des cellules hépatiques dans l'espace de Disse et dans l'espace intercellulaire élargi entre deux cellules hépatiques voisines. Outre la prolifération de canaux biliaires. La prolifération de cellules mésenchymales, la néoformation de fibres et la nécrobiose sont interprétés comme l'expression d'une cirrhose hépatique. Resumen Exámenes foto y electrónicoópticos de la cirrosis hepática tras intoxicación experimental con aflatoxina en patipollos En dos grupos de ensayo (0,03 mg y 0,01 mg cada 2° dí...

show abstract

Groundnut Toxicity in Poultry:

Cited by 2 publications

References 2 publications

Aflatoxins: History, Significant Milestones, Recent Data on Their Toxicity and Ways to Mitigation

Aflatoxins: History, Significant Milestones, Recent Data on Their Toxicity and Ways to Mitigation

Licht‐ und elektronenoptische Untersuchungen zur Leberzirrhose nach experimenteller Aflatoxinvergiftung bei Entenküken

Contact Info

Product

Resources

About