Abstract. Ground state cooling and coherent manipulation of ions in an rf-(Paul) trap is the prerequisite for quantum information experiments with trapped ions. With resolved sideband cooling on the optical S 1/2 -D 5/2 quadrupole transition we have cooled one and two 40 Ca + ions to the ground state of vibration with up to 99.9% probability. With a novel cooling scheme utilizing electromagnetically induced transparency on the S 1/2 -P 1/2 manifold we have achieved simultaneous ground state cooling of two motional sidebands 1.7 MHz apart. Starting from the motional ground state we have demonstrated coherent quantum state manipulation on the S 1/2 -D 5/2 quadrupole transition at 729 nm. Up to 30 Rabi oscillations within 1.4 ms have been observed in the motional ground state and in the n = 1 Fock state. In the linear quadrupole rf-trap with 700 kHz trap frequency along the symmetry axis (2 MHz in radial direction) the minimum ion spacing is more than 5 µm for up to 4 ions. We are able to cool two ions to the ground state in the trap and individually address the ions with laser pulses through a special optical addressing channel.