Gross pathology and histopathology of haemonchosis in sheep and goats in Iraq

Al-Zubaidy, A.J.; Altaif, K. I.; Al-Qaisy, H.H.K.; Makkawi, T.A.

doi:10.1016/0304-4017(87)90010-0

Cited by 16 publications

(14 citation statements)

References 6 publications

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“…Abomasal changes were observed mainly in gastric folds at 3 and 7 wpi, agreeing with the findings reported previously in sheep and goats experimentally infected with H. contortus [1,15,28,30]. At 3 wpi, larvae were observed within deep areas of the abomasal mucosa, a location previously reported in goats infected with H. contortus of ovine origin, whereas in sheep larvae showed tropism for superficial areas of the mucosa [1].…”

Section: Discussionsupporting

confidence: 90%

“…The increase staining for mucous secretion in abomasal glands was marked at 3, very marked at 7 wpi, and moderate at 21 wpi, when the number of worms recorded was low. Similar findings have been reported in goats [1] and adult sheep, whereas in young lambs without resistance to H. contortus, a decrease in detectable mucus was found [30].…”

Section: Discussionsupporting

confidence: 89%

“…The abomasal infiltrate of eosinophils was heavy at 3 and 7 wpi, coinciding with previous finding in goats [1,28] and sheep [12,15,29] infected with H. contortus and goats infected with Teladorsagia circumcincta and Trichostrongylus vitrinus [21]. Eosinophils have been related with mechanisms of resistance against H. contortus in sheep, since they were absent in young lambs and susceptible breeds, but abundant in resistant breeds [12,30].…”

Section: Discussionsupporting

confidence: 87%

“…On the other hand, the host response may have induced death of some larvae within the abomasal mucosa, as suggested the presence of degenerated larvae surrounded by lymphocytes and eosinophils by 3 wpi, and granulomas by 3 and 7 wpi. These granulomas have not been reported in sheep and goats infected with H. contortus, although whitish spots or plaques were described in goats at 21 days post-infection [1]. Further studies at early stages post-infection and with reinfected goats are of interest to better investigate the relationship between presence of abomasal granulomas and the mechanism of protection against H. contortus infection.…”

Section: Discussionmentioning

confidence: 93%

“…In contrast, little is known about the pathogenesis and host response against gastrointestinal nematode in goats. Few studies have investigated the host response to Trichostrongylus vitrinus and Teladorsagia circumcincta [16,21] and some experimental studies have been carried out to analyse the effects of H. contortus infection on milk production [14], and the gross and histopathological changes induced from 4 to 21 days post-infection [1]. Recently, clinical, parasitological and serum parasite-specific IgG responses were examined in goats after primary and secondary H. contortus infections [6].…”

Section: Introductionmentioning

confidence: 99%

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Pathological and immunohistochemical study of the abomasum and abomasal lymph nodes in goats experimentally infected with Haemonchus contortus

Pérez¹,

García²,

Hernández³

et al. 2001

Vet. Res.

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Histopathological changes and the distributions of T and B lymphocytes and IgG producing plasma cells were recorded in the abomasum and abomasal lymph nodes of goats 3, 7 and 21 weeks post-infection (wpi) after an experimental infection with H. contortus. The low rate of worm recovery by 3 wpi (5.6%) might have been due to larvae death as suggested by the presence of granulomas in the abomasal mucosa at 3 and 7 wpi, or simply due to a poor larval establishment. Marked increase in the secretion of mucus by mucous cells together with an abundant infiltration of eosinophils, mast cells, CD3+ T lymphocytes, CD79a+ B cells, IgG+ plasma cells and globule leukocytes were recorded in the abomasal mucosa, especially at 7 wpi. Except for the globule leukocytes, this reaction decreased substantially by week 21, suggesting this cell type may have been involved in rejection of adult nematodes. The abomasal lymph nodes showed marked hyperplasia, particularly of CD79a+ B cells and IgG+ plasma cells in all infected goats. These reactions may have been responsible for the reduction in the number of worms found in the abomasum between 3 and 7 wpi.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Pathological and immunohistochemical study of the abomasum and abomasal lymph nodes in goats experimentally infected with Haemonchus contortus

Pérez¹,

García²,

Hernández³

et al. 2001

Vet. Res.

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Gastrointestinal parasitic infections in Indian Gaddi (goat) breed bucks: clinical, hemato-biochemical, parasitological and chemotherapeutic studies

et al. 2017

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The present study was envisaged with an aim to evaluate gastrointestinal parasitic infections in a herd of conserved Gaddi (goat) breed bucks (6-9 months of age) kept on semi-intensive feeding management. The individuals (n = 20) representing the herd were selected and divided into two groups; group I (n = 10), clinically ill and group II (n = 10), sub clinically infected individuals. The clinical examination revealed anemia, emaciation and rise in body temperature of the individuals of group I as compared to group II. The detailed copro-parasitological examination and copro-culture revealed the presence of eggs of and larvae of species, respectively in the fecal samples of both clinically and sub clinically infected individuals. The hemato-biochemical parameters proved vital indicators of the health of group I individuals and exhibited decline in the values of hemoglobin, packed cell volume and total erythrocyte count as compared to group II. Significant ( < 0.05) hypoproteinemia, hypoalbuminemia, hypoglycemia and increased levels of alanine aminotransferase and aspartate aminotransferase were observed in infected individuals as compared to treated ones. The detailed parasitological, hemato-biochemical observations and clinical findings elucidated and supported the presence of concurrent gastrointestinal parasitism in the herd. The significant improvement was observed in the health status of the herd after 1 month of the therapeutic management, which was carried out using a combination of fenbendazole and praziquantel in both clinically and sub clinically infected individuals.

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Changes in liveweight gain, blood constituents and worm egg output in goats artificially infected with a sheep-derived strain of Haemonchus contortus

Rahman

Collins

1990

British Veterinary Journal

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Gross pathology and histopathology of haemonchosis in sheep and goats in Iraq

Cited by 16 publications

References 6 publications

Pathological and immunohistochemical study of the abomasum and abomasal lymph nodes in goats experimentally infected with Haemonchus contortus

Pathological and immunohistochemical study of the abomasum and abomasal lymph nodes in goats experimentally infected with Haemonchus contortus

Gastrointestinal parasitic infections in Indian Gaddi (goat) breed bucks: clinical, hemato-biochemical, parasitological and chemotherapeutic studies

Changes in liveweight gain, blood constituents and worm egg output in goats artificially infected with a sheep-derived strain of Haemonchus contortus

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