Gross Abnormalities of the Umbilical Cord: Related Placental Histology and Clinical Significance

Tantbírójn, Patou; Saleemuddin, Aasia; Sirois, Katia; Crum, Christopher P.; Boyd, Theonia K.; Tworoger, Shelley S.; Parast, Mana M.

doi:10.1016/j.placenta.2009.09.005

Cited by 135 publications

(96 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, none of the placentas from healthy babies had placental intravascular thrombi (p<0.05). In contrast, occlusion of <50% of the lumen are not uncommon at term and this is reported to be a preparation for parturition (8). Table 2.…”

Section: Discussionmentioning

confidence: 99%

“…Unexplained fetal loss includes stillbirths associated with growth restriction and placental abruption (6). Information on placental abnormalities may reveal the presence of chronic fetal insults and allow their differentiation from acute (peripartum) stresses (8). The aim of the present study is to analyze histological changes in placentas of IUGR fetuses, in placentas of unexplained intrauterine death fetuses and in uncomplicated pregnancies.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Histopathological analysis of the placental lesions in pregnancies complicated with IUGR and stillbirths in comparison with noncomplicated pregnancies

Günyeli¹,

Erdemoğlu²,

Ceylaner³

et al. 2011

J Turkish German Gynecol Assoc

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Histopathological analysis of the placental lesions in pregnancies complicated with IUGR and stillbirths in comparison with noncomplicated pregnancies

Günyeli¹,

Erdemoğlu²,

Ceylaner³

et al. 2011

J Turkish German Gynecol Assoc

View full text Add to dashboard Cite

“…Gross cord abnormalities predispose the foetus to stasis-induced vascular ectasia and thrombosis, thus leading to vascular obstruction and adverse neonatal outcome, including IUGR and still-birth [17].…”

Section: Discussionmentioning

confidence: 99%

Perinatal Mortality and Umbilical Cord Parameters: Is there Any Association?

Soliriya¹,

Goyal²,

Kachhawaha³

2017

J Preg Child Health

View full text Add to dashboard Cite

Introduction: Abnormal cord parameters associate with high rate of asphyxia during delivery, foetal anomalies, non-reassuring foetal status, respiratory distress, foetal growth restriction and delivery interventions.Objective: To study the correlation between umbilical cord parameters and perinatal mortality. Materials and methods:This was a prospective study carried out in the Umaid Hospital, Dr. S N Medical College, Jodhpur from March-2014 to November-2014. It included 500 cases admitted to labour room with period of gestation >37 weeks. Details of delivery of baby including mode of delivery, Apgar score, NICU admission and any congenital anomaly found in unbooked cases post-natally was noted down. Umbilical cord parameters were also noted and correlated with perinatal outcome using Fischer's exact test and Chi square test. Results:Out of 500 cases, the cord length was normal in 88.2% cases while it was short in 6.2% and long in 5.6% cases. True knots were associated with a higher mean cord length of 95.83 ± 24.99 cm. The difference of mean cord length between single loop and more than two loops was highly significant (p value<0.001). Cesarean section rate was found to be significantly different between one loop and more than two loops (p<0.001). Conclusion:The excessively long cords are associated with cord prolapse, true knot and poor fetal outcome and increased operative interference. Short cords are associated with failed progress, cord rupture and congenital malformations. Nuchal cords are responsible for threatening fetal well being along with other placental as well as intrapartum factors for poor fetal outcome parameters of umbilical cord were examined at the time of delivery and after delivery: presence of any loop around neck, trunk, shoulder, etc. cord loops tight or loose in LSCS cases, number of loops of cord and positions, knots of cord (true or false), length and diameter of umbilical cord. Amongst these, we have excluded hypo and hypercoiled cords as there is much fluctuation in the number of coils with passage of time, postnatally. Determination of length of umbilical cord was done after the delivery of fetus, cord was clamped at two places and cut in between. From the cut end up to fetal umbilicus and placental attachment umbilical cord, length was measured with flexible tape in cm and added. A data check sheet was maintained for each case till completion of delivery. The umbilical cord length measurements were categorized into short, when the measured length was <39 cm, normal, when the measurement was between 39 to 95 cm and long cord if the measurement was >95 cm [1,2]. Statistical analysis was performed using SPSS17.0 for windows. The sample size of the study was calculated as 400 taking the power as 90% and 20% dropout. Continuous data were analyzed by t-test and categorical data by using Chi-square test or Fisher exact test. J Preg Child Health, an open access journal

show abstract

“…al. reported that gross cord abnormalities including long cords were associated with stillbirth, intrauterine growth restriction, non- reassuring fetal tracing, meconium-stained amniotic fluid, and increased rate of emergency cesarean section [7]. These emergency conditions should be managed appropriately to prevent severe outcomes.…”

Section: Discussionmentioning

confidence: 99%

Oligohydramnios associated with a long umbilical cord

Bashiri

Mf²,

Oligohydramnios³

et al. 2011

IJCRI

View full text Add to dashboard Cite

Introduction: Oligohydramnios is defined by ultrasound as 'AFI of 5 cm or less' and it can be associated with adverse perinatal outcome. Case Report: We present a case of primiparous women that was found to have oligohydramnios with amniotic fluid index fluctuations.Although the differential diagnosis includes several serious conditions, a unique cause was found -a long cord at the delivery, over 120 cm. This Finding can explain the oligohydramnios by ultrasound. Since the long cord was occupying the majority of pockets used for measurements, it was impossible to measure amniotic fluid pockets without cord. Conclusion: Thus, the oligohydramnios was not a true one but rather a technical problem which was confirmed by the normal amount of amniotic fluid volume found at delivery.

show abstract

Gross Abnormalities of the Umbilical Cord: Related Placental Histology and Clinical Significance

Cited by 135 publications

References 17 publications

Histopathological analysis of the placental lesions in pregnancies complicated with IUGR and stillbirths in comparison with noncomplicated pregnancies

Histopathological analysis of the placental lesions in pregnancies complicated with IUGR and stillbirths in comparison with noncomplicated pregnancies

Perinatal Mortality and Umbilical Cord Parameters: Is there Any Association?

Oligohydramnios associated with a long umbilical cord

Contact Info

Product

Resources

About