“…Fifteen studies reporting on a subset of outcomes for 13 different interventions met our inclusion criteria: TF-CBT, cognitive processing therapy, narrative exposure therapy (NET), grief-and trauma-focused intervention (GTFI) group and GTFI with coping skills and narrative processing, emotional regulation therapy, eye movement desensitization and reprocessing (EMDR), cognitive-behavioral intervention for trauma in schools (CBITS), trauma and grief component therapy; school group with elements of CBT; imipramine; fluoxetine; and sertraline ( 28,35 Three interventions used active comparators: 1 trial compared outcomes for NETwith meditation-relaxation therapy outcomes, 24 1 GTFI study compared group therapy with individual therapy, 25 and 1 trial examined outcomes for GTFI with coping skills and narrative processing versus GTFI with coping skills only. 38 Three of 13 interventions focused on medications: imipramine versus chloral hydrate, 31 imipramine versus fluoxetine and placebo, 32 and sertraline versus placebo. 33 As with the cluster of studies reporting on interventions targeting children exposed to trauma, no pharmacological interventions found any evidence of benefit, and the sertraline study suggested that children in the intervention arm fared worse than those in the control arm.…”