Grids I: Electrophilic Aromatic Substitution

Abstract

El efecto de los sustituyentes en la reactividad de la sustitución electrofílica aromática ha sido organizado en cuadrículas para demostrar los efectos de inducción y resonancia. Este esquema podría incorporar la competencia entre donación y extracción de la densidad electronica. Proponemos actividades en clase, en las cuales los estudiantes pueden practicar los efectos mientras están jugando.

H-Bridges with OH Donors in Organic Chemistry

“…-OR, -NR 2 ) provides a better acceptor, whereas electron-withdrawing groups (e.g. -NO 2 , carbonyl) inhibit the formation of H-bridges (Lamoureux & Arias-Álvarez, 2020).…”

Grids III: Hydrogen Bridges in Introductory Chemistry

“…"Two significant challenges [are] faced by chemistry instructors: i) to graphically represent forces of attraction between molecules and ii) to develop the imagery that in the liquid state, orientation of molecules toward each other because of polarities is transitory." (Bucat & Mocerino, 2009) Grids have been shown to be very useful for the organization of inductive and resonance effects for Electrophilic Aromatic Substitution (Lamoureux & Arias-Álvarez, 2020) and Aromatic Acidity and Basicity (Lamoureux & Arias-Álvarez, 2021). The separation of chemistry data in two-dimensions, and the use of color to indicate trends within the data, provides a different perspective than memorization of a list.…”