Green3: A green extraction of green additives for green plastics

Muccilli, Vera; Maccarronello, Anna E.; Rasoanandrasana, Carolle; Cardullo, Nunzio; de Luna, Martina S.; Pittalà, Maria G.G.; Riccobene, Paolo M.; Carroccio, Sabrina C.; Scamporrino, Andrea A.

doi:10.1016/j.heliyon.2024.e24469

Heliyon

2024

DOI: 10.1016/j.heliyon.2024.e24469

|View full text |Cite

Green3: A green extraction of green additives for green plastics

Vera Muccilli,

Anna E. Maccarronello,

Carolle Rasoanandrasana

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite1

Independent1

Authors

Journals

Cited by 2 publications

References 54 publications

(58 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Flavonoids with lipase inhibitory activity from lemon squeezing waste: isolation, multispectroscopic and in silico studies

Cardullo,

Calcagno,

Pulvirenti

et al. 2024

J Sci Food Agric

Self Cite

View full text Add to dashboard Cite

BACKGROUNDObesity is recognized as a lifestyle‐related disease and the main risk factor for a series of pathological conditions, including cardiovascular diseases, hypertension and type 2 diabetes. Citrus limon is an important medicinal plant, and its fruits are rich in flavonoids investigated for their potential in managing obesity. In the present work, a green extraction applied to lemon squeezing waste (LSW) was optimized to recover pancreatic lipase (PL) inhibitors.RESULTSThe microwave‐assisted procedure yielded an extract with higher lipase inhibitory activity than those obtained by maceration and ultrasound. The main compounds present in the extract were identified by high‐performance liquid chromatographic–mass spectrometric analysis, and hesperidin, eriocitrin and 4′‐methyllucenin II were isolated. The three compounds were evaluated for in vitro PL inhibitory activity, and 4′‐methyllucenin II resulted in the most promising inhibitor (IC50 = 12.1 μmol L−1; Ki = 62.2 μmol L−1). Multispectroscopic approaches suggested the three flavonoids act as competitive inhibitors and the binding studies indicated a greater interaction between PL and 4′‐methyllucenin II. Docking analysis indicated the significant interactions of the three flavonoids with the PL catalytic site.CONCLUSIONThe present work highlights flavonoid glycosides as promising PL inhibitors and proposes LSW as a safe ingredient for the preparation of food supplements for managing obesity. © 2024 Society of Chemical Industry.

show abstract

Flavonoids with lipase inhibitory activity from lemon squeezing waste: isolation, multispectroscopic and in silico studies

Cardullo,

Calcagno,

Pulvirenti

et al. 2024

J Sci Food Agric

Self Cite

View full text Add to dashboard Cite

show abstract

Isosorbide as a building block for Poly(butylene adipate-co-terephthalate)-based copolyesters with enhanced mechanical properties and tunable biodegradability

Liu,

Zhou,

Yang

et al. 2024

Polymer Degradation and Stability

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Green3: A green extraction of green additives for green plastics

Cited by 2 publications

References 54 publications

Flavonoids with lipase inhibitory activity from lemon squeezing waste: isolation, multispectroscopic and in silico studies

Flavonoids with lipase inhibitory activity from lemon squeezing waste: isolation, multispectroscopic and in silico studies

Isosorbide as a building block for Poly(butylene adipate-co-terephthalate)-based copolyesters with enhanced mechanical properties and tunable biodegradability

Contact Info

Product

Resources

About