Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health

Opuwari, Chinyerum Sylvia; Monsees, Thomas K.

doi:10.1038/s41598-020-72319-6

Cited by 27 publications

(25 citation statements)

References 93 publications

(141 reference statements)

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“…Consistently, the ad libitum administration of 2% and 5% aqueous extract of green tea for 52 days increased sperm concentration and viability in rats, [ 136 ]. In the same study, the authors revealed spontaneous acrosome reaction and morphological changes in testis and epidydimis, with increased cauda epididymis epithelial height and decreased diameter and epithelial height of seminiferous tubules [ 136 ]. Similar effects on sperm vitality, motility, acrosome reaction, and morphological parameters in the seminiferous tubules and epididymis were observed following black tea administration [ 137 ].…”

Section: Action Of Polyphenols On Some Hallmarks Of Agingmentioning

confidence: 86%

“…For example, tea polyphenols, known as catechins, decreased the apoptosis rate of spermatogenic cells in rats with experimental varicocele [135]. Consistently, the ad libitum administration of 2% and 5% aqueous extract of green tea for 52 days increased sperm concentration and viability in rats, [136]. In the same study, the authors revealed spontaneous acrosome reaction and morphological changes in testis and epidydimis, with increased cauda epididymis epithelial height and decreased diameter and epithelial height of seminiferous tubules [136].…”

Section: Polyphenols and Male Fertilitymentioning

confidence: 97%

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Impact of Polyphenolic-Food on Longevity: An Elixir of Life. An Overview

Meccariello

D’Angelo

2021

Antioxidants

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Aging and, particularly, the onset of age-related diseases are associated with tissue dysfunction and macromolecular damage, some of which can be attributed to accumulation of oxidative damage. Recently, growing interest has emerged on the beneficial effects of plant-based diets for the prevention of chronic diseases including obesity, diabetes, and cardiovascular disease. Several studies collectively suggests that the intake of polyphenols and their major food sources may exert beneficial effects on improving insulin resistance and related diabetes risk factors, such as inflammation and oxidative stress. They are the most abundant antioxidants in the diet, and their intake has been associated with a reduced aging in humans. Polyphenolic intake has been shown to be effective at ameliorating several age-related phenotypes, including oxidative stress, inflammation, impaired proteostasis, and cellular senescence, both in vitro and in vivo. In this paper, effects of these phytochemicals (either pure forms or polyphenolic-food) are reviewed and summarized according to affected cellular signaling pathways. Finally, the effectiveness of the anti-aging preventive action of nutritional interventions based on diets rich in polyphenolic food, such as the diets of the Blue zones, are discussed.

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Section: Action Of Polyphenols On Some Hallmarks Of Agingmentioning

confidence: 86%

Section: Polyphenols and Male Fertilitymentioning

confidence: 97%

Impact of Polyphenolic-Food on Longevity: An Elixir of Life. An Overview

Meccariello

D’Angelo

2021

Antioxidants

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“…However, a significant increase in spontaneous acrosome reactions was observed. Finally, the antioxidant defenses (CAT, GSH, MDA, and SOD levels) remain unchanged, indicating the safety of green tea consumption and a balance of the oxidative stress status of the tissues [158].…”

Section: Green Teamentioning

confidence: 99%

Natural Products as Protective Agents for Male Fertility

Martins

Silva

Duarte

et al. 2021

BioChem

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The male reproductive system is highly susceptible to noxious influences, such as oxidative stress, inflammation, drugs, and even diseases that can induce germ cell damage and alterations in spermatogenesis. All of these factors, which are caused by actions at the testicular level and/or at the excurrent ducts and accessory glands, significantly affect sperm parameters and male fertility. For this reason, it is of major importance to investigate possible ways to protect the male reproductive system since males are exposed to these toxic factors constantly. For centuries, natural products have been used by humans in folk medicine as therapeutic agents, and because of their beneficial properties for human health, plenty of them have been introduced to the pharmaceutical market as supplementary therapies. The present review aims to compile available information regarding different natural exogenous factors that demonstrate potential useful activity in the male reproductive system. The studies presented here reopen the perspective of using natural products as protective agents and eventually as new supplementary therapeutic options for the recovery of hampered spermatogenesis and/or male infertility.

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“…On the other hand, a certain physiological amount of ROS activity is essential for spermatogenesis and normal sperm functions. Thus, excessive use of antioxidants can have a negative effect on spermatogenesis and male fertility [65,66]. This might be the reason as to why Aboua et al [67] noted a significant decline in the motility of spermatozoa in vitro after exposure to RPO.…”

Section: Red Palm Oil In Male Infertility Preventionmentioning

confidence: 99%

Role of Red Palm Oil in Male Obesity and Infertility Prevention

Olabiyi¹,

Aboua²,

Monsees³

2022

Elaeis Guineensis

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The African continent has wide, varied, and rich plant diversity due to its climate. Some of these plants and their products have received tremendous attention due to their benefits in treating and managing ailments that plagues humanity. Red palm oil (RPO) is one of such natural products that have immense nutritional value with ability to ameliorate cardiac- and reproductive-related disorders. In this review article, the current knowledge on the potential of RPO as a phytomedicine to lessen or even prevent the negative impact of obesity on general health status and male fertility was evaluated. This study was done using electronic databases such as PubMed, Scopus, Science Direct, Google Scholar and Web of Science. The study revealed some controversies and inconsistent reports on the effect of RPO on obesity and male fertility which needs further research using appropriate experimental models of obesity. Obesity is known to disrupt male fertility by causing changes to the hypothalamic- pituitary-gonadal axis, thus impairing steroidogenesis and spermatogenesis. As spermatozoa are extremely sensitive towards oxidative stress, a carefully balanced daily supplementation of normal diet with antioxidant-rich RPO might be useful to protect spermatozoa and preserving male fertility. RPO was shown to be useful to protect against or ameliorate toxin- or medical condition-induced male infertility. Also, RPO is packed with powerful antioxidants like carotenoids and vitamin E which helps to prevent cell damage. However, its role in obesity prevention remains a debate.

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Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health

Cited by 27 publications

References 93 publications

Impact of Polyphenolic-Food on Longevity: An Elixir of Life. An Overview

Impact of Polyphenolic-Food on Longevity: An Elixir of Life. An Overview

Natural Products as Protective Agents for Male Fertility

Role of Red Palm Oil in Male Obesity and Infertility Prevention

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