Green Tea Consumption and Mortality Due to Cardiovascular Disease, Cancer, and All Causes in Japan

Kuriyama, Shinichi; Shimazu, Taichi; Ohmori, Kenji; Kikuchi, Nobutaka; Nakaya, Naoki; Nishino, Yoshikazu; Tsubono, Yoshitaka; Tsuji, Ichiro

doi:10.1001/jama.296.10.1255

Cited by 687 publications

(530 citation statements)

References 24 publications

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“…Although the reason is unclear, various hypotheses have been proposed, e.g. low serum cholesterol levels in Japanese in 1980 compared with westernised countries [11], as well as levels of fish [26] or green tea intake [27] among the Japanese.…”

Section: Discussionmentioning

confidence: 99%

Relationship of elevated casual blood glucose level with coronary heart disease, cardiovascular disease and all-cause mortality in a representative sample of the Japanese population. NIPPON DATA80

et al. 2008

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Aims/hypothesis High fasting blood glucose is one of the well-known risk factors for CHD. However, in certain settings, patients cannot always be expected to fast. For example, community screenings for cardiovascular disease (CVD) risk factors in Japan are performed under non-fasting conditions to achieve high participation rates. Thus, we examined a representative cohort of the Japanese population (n=9,444, follow-up period 17.3 years) to clarify whether high casual blood glucose (CBG) can predict CVD mortality. Methods We defined CBG groups as follows: high CBG≥ 11.1 mmol/l or participants with a history of diabetes mellitus; borderline high, 7.77≤CBG<11.1 mmol/l; higher normal, 5.22≤CBG<7.77 mmol/l); and lower normal, CBG<5.22 mmol/l. The multivariate-adjusted hazard ratios (HRs) for CHD, CVD and all-cause mortality were calculated. Results The crude CHD mortality rate was 0.84 per 1,000 person-years. Age-and sex-adjusted HRs for CHD mortality were high among participants with CBG levels ≥7.77 mmol/l, regardless of time since last meal. Multivariate-adjusted HRs (95% CI) of CHD mortality in high and borderline high CBG groups were 2.62 (1.46-4.67) and 2.43 (1.29-4.58), respectively. Similar results were observed for both CVD Diabetologia (2008) and all-cause mortality. Even within the normal blood glucose range, each 1 mmol/l increase in CBG was associated with a statistically significant increase in the HR for CVD mortality (1.12, 95% CI 1.02-1.22). Population-attributable fractions of the combined groups of high and borderline high CBG for CHD, CVD and all-cause mortality were 12.0, 4.9 and 3.5%, respectively. Conclusions/interpretation Increases in CBG, even within the normal range, predict CVD mortality.51:575-582 DOI 10.1007/s00125-007-0915-6 Electronic supplementary

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Section: Discussionmentioning

confidence: 99%

Relationship of elevated casual blood glucose level with coronary heart disease, cardiovascular disease and all-cause mortality in a representative sample of the Japanese population. NIPPON DATA80

et al. 2008

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“…While epidemiological studies point to the notion that consuming flavonoid-rich food or beverages may prolong human lifespan by lowering cardiovascular mortality (21) or improving insulin sensitivity (22) , some of these studies also show that flavonoid subclasses (flavanols, catechins)…”

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confidence: 99%

A literature review of flavonoids and lifespan in model organisms

Pallauf¹,

Duckstein²,

Rimbach³

2016

Proc. Nutr. Soc.

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Epidemiological data on consumption of flavonoid-containing food points to the notion that some of these secondary plant metabolites may favour healthy ageing. The aim of the present paper was to review the literature on lifespan extension by flavonoids in worms, flies and mice. In most studies, worms and flies experienced lifespan extension when supplemented with flavonoids either as extracts or single compounds. Studies with mutant worms and flies give hints as to which gene products may be regulated by flavonoids and consequently enhance longevity. We discuss the data considering putative mechanisms that may underlie flavonoid action such as energy-restriction-like effects, inhibition of insulin-like-growth-factor signalling, induction of antioxidant defence mechanisms, hormesis as well as antimicrobial properties. However, it remains uncertain whether human lifespan could be prolonged by increased flavonoid intake.

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“…The current study explores the connection between consumption of chamomile tea and 7-year all-cause mortality in a sample of older Mexican American adults residing in the Southwestern United States. Given the results from other cohort studies on the health protective effects of consumption of black and green tea (KrisEtherton & Keen, 2002;Kuriyama et al, 2006;Peters et al, 2001;Tsubono et al, 2001;Zheng et al, 1996) as well as the broad biological effects of chamomile and potential for cardiovascular and cancer risk reduction, we hypothesized that consumption of chamomile tea would be associated with reduced all-cause mortality and possibly cardiovascular and cancer mortality in Mexican origin older adults. We also hypothesized that, due to gender differences in the rate of chamomile consumption, the effect of chamomile on mortality would be different for men and women.…”

Section: Health Benefits Of Chamomilementioning

confidence: 99%

“…Tea consumption, both black and green, has been linked to a lower risk of mortality, reduced cardiovascular events, and reduced incidence of some cancers (Cooper, Morre, & Morre, 2005;Iwai et al, 2002;KrisEtherton & Keen, 2002;Kuriyama et al, 2006;Tsubono et al, 2001;Zaveri, 2006;Zheng et al, 1996). A report on the effects of green tea on all-cause and cause-specific mortality of adults in Japan suggested that consumption of three or more cups of green tea per day was associated with…”

mentioning

confidence: 99%

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Chamomile Consumption and Mortality: A Prospective Study of Mexican Origin Older Adults

Howrey

Peek

McKee

et al. 2015

GERONT

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Purpose: Approximately 20% of adults use some kind of herbal; however, little data exists from population-based study or clinical trials to support effectiveness of most herbal products. Chamomile is a commonly used herb among older adults of Mexican origin. We examined the effects of herbal chamomile consumption on mortality among older adults of Mexican origin. Methods and Design: A sample from the Hispanic Established Populations for Epidemiologic Study of the Elderly, a population-based study of noninstitutionalized Mexican Americans aged 65 and older from five Southwestern states (Texas, California, New Mexico, Colorado, and Arizona). We included all men and women from 2000 to 2007 (n = 1,677). Results: Chamomile was used by 14% of the sample. Cox proportional hazards regression analyses showed that chamomile was associated with a decreased risk of mortality in the total sample (hazard ratio [HR] 0.71, 95% confidence interval [CI] 0.55-0.92) and for women (HR 0.67, 95% CI 0.49-0.92) but not for men. In models adjusted for sociodemographic variables, health behaviors, and chronic conditions, chamomile remained significantly associated with reduced mortality in women (HR 0.72,. Implications: The use of chamomile shows protective effects against mortality in this sample of older adults of Mexican origin for women. Further research is warranted in other populations to determine if these effects are consistent.

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Green Tea Consumption and Mortality Due to Cardiovascular Disease, Cancer, and All Causes in Japan

Abstract: Green tea consumption is associated with reduced mortality due to all causes and due to cardiovascular disease but not with reduced mortality due to cancer.

Cited by 687 publications

References 24 publications

Relationship of elevated casual blood glucose level with coronary heart disease, cardiovascular disease and all-cause mortality in a representative sample of the Japanese population. NIPPON DATA80

Relationship of elevated casual blood glucose level with coronary heart disease, cardiovascular disease and all-cause mortality in a representative sample of the Japanese population. NIPPON DATA80

A literature review of flavonoids and lifespan in model organisms

Chamomile Consumption and Mortality: A Prospective Study of Mexican Origin Older Adults

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