Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project

Kuriyama, Shinichi; Hozawa, Atsushi; Ohmori, Kenji; Shimazu, Taichi; Matsui, Toshifumi; Ebihara, Satoru; Awata, Shuichi; Nagatomi, Ryoichi; Arai, Hiroyuki; Tsuji, Ichiro

doi:10.1093/ajcn/83.2.355

Cited by 367 publications

(249 citation statements)

References 32 publications

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“…Conversely, a Japanese study (13) found no association between coffee consumption and depressive symptoms. The lack of an association in the Japanese study may be partly ascribed to infrequent consumption of coffee among the elderly, with only 13?2 % of the study participants consuming $2 cups coffee/d, as reported in an earlier study that included the same participants (30) . A null finding has also been reported from a Finnish study (18) .…”

Section: Discussionmentioning

confidence: 67%

Green tea and coffee consumption is inversely associated with depressive symptoms in a Japanese working population

Pham

Nanri

Kurotani

et al. 2013

Public Health Nutr.

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Objective: To examine the association between the consumption of green tea, coffee and caffeine and depressive symptoms. Design: Cross-sectional study. Consumption of green tea and coffee was ascertained with a validated dietary questionnaire and the amount of caffeine intake was estimated from these beverages. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Multiple logistic regression analysis was performed to compute odds ratios and 95 % confidence intervals for depressive symptoms with adjustments for potential confounders. Setting: Two workplaces in north-eastern Kyushu, Japan, in 2009. Subjects: A total of 537 men and women aged 20-68 years. Results: Higher green tea consumption was associated with a lower prevalence of depressive symptoms. Compared with participants consuming #1 cup/d, those consuming $4 cups green tea/d had a 51 % significantly lower prevalence odds of having depressive symptoms after adjustment for potential confounders, with significant trend association (P for trend 5 0?01). Further adjustment for serum folate slightly attenuated the association. Coffee consumption was also inversely associated with depressive symptoms ($2 cups/d v. ,1 cup/d: OR 5 0?61; 95 % CI 0?38, 0?98). Multiple-adjusted odds for depressive symptoms comparing the highest with the lowest quartile of caffeine consumption was OR 5 0?57 (95 % CI 0?30, 1?05; P for trend 5 0?02). Conclusions: Results suggest that higher consumption of green tea, coffee and caffeine may confer protection against depression.

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Section: Discussionmentioning

confidence: 67%

Green tea and coffee consumption is inversely associated with depressive symptoms in a Japanese working population

Pham

Nanri

Kurotani

et al. 2013

Public Health Nutr.

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“…The first study analyzed data from 1003 Japanese subjects (470 years), who gave information about the frequency of green tea consumption, whereas their cognitive function was evaluated by using the Mini-Mental State Examination test. 4 The authors found that higher consumption of green tea is associated with a lower prevalence of cognitive impairment. Comparable results were obtained in another study including 2501 Chinese aged 455 years.…”

Section: Introductionmentioning

confidence: 99%

Neural effects of green tea extract on dorsolateral prefrontal cortex

et al. 2012

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BACKGROUND/OBJECTIVES: Green tea is being recognized as a beverage with potential benefits for human health and cognitive functions. In vivo studies provide preliminary evidence that green tea intake may have a positive role in improving effects on cognitive functions. We aimed to examine the neural effects of green tea extract on brain activation in humans. SUBJECTS/METHODS: Functional magnetic resonance imaging was recorded while 12 healthy volunteers performed a working memory task following administration of 250 or 500 ml of a milk whey based green tea containing soft drink or milk whey based soft drink without green tea as control in a double-blind, controlled repeated measures within-subject design with counterbalanced order of substance administration. A whole-brain analysis with a cluster-level threshold of Po0.001 (unadjusted) was followed by an a priori-defined region of interest (ROI) analysis of the dorsolateral prefrontal cortex (DLPFC) including a cluster-level threshold of Po0.05 and family-wise error (FWE) adjustment for multiple comparisons. RESULTS: Whole-brain analyses revealed no significant effects after correction for multiple comparisons (FWE Po0.05). Using a ROI approach, green tea extract increased activation in the DLPFC relative to a control condition (FWE Po0.001). This neural effect was related to green tea dosage. Green tea extract was not associated with any significant attenuation in regional activation relative to control condition. CONCLUSIONS: These data suggest that green tea extract may modulate brain activity in the DLPFC, a key area that mediates working memory processing in the human brain. Moreover, this is the first neuroimaging study implicating that functional neuroimaging methods provide a means of examining how green tea extract acts on the brain.

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“…Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924No /2006. This opinion addresses the scientific substantiation of health claims in relation to L-theanine from Camellia sinensis (L.) Kuntze (tea) and improvement of cognitive function, alleviation of psychological stress, maintenance of normal sleep and reduction of menstrual discomfort.…”

Section: Discussionmentioning

confidence: 99%

Scientific Opinion on the substantiation of health claims related to L-theanine from Camellia sinensis (L.) Kuntze (tea) and improvement of cognitive function (ID 1104, 1222, 1600, 1601, 1707, 1935, 2004, 2005), alleviation of psychological stress (ID 159

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EFSA Journal

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SUMMARYFollowing a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924No /2006. This opinion addresses the scientific substantiation of health claims in relation to L-theanine from Camellia sinensis (L.) Kuntze (tea) and improvement of cognitive function, alleviation of psychological stress, maintenance of normal sleep and reduction of menstrual discomfort. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders.The food/constituents that are the subject of the health claims are Camellia sinensis (L.) Kuntze (tea) and L-theanine. The Panel considers that while Camellia sinensis (L.) Kuntze (tea) is not sufficiently characterised in relation to the claimed effects, L-theanine from Camellia sinensis (L.) Kuntze (tea) is sufficiently characterised. Improvement of cognitive functionThe claimed effects are "physical and mental stimulation (hydration and caffeine)", "mental and cognitive health", "cognitive function", "neurological functions", "physiological antagonistic against caffeine", and "cognitive performance: focussed attention". The target population is assumed to be the general population. In the context of the proposed wordings and clarifications from Member States, the Panel assumes that the claimed effects refer to improvement of cognitive function. The Panel considers that improvement of cognitive function is a beneficial physiological effect.In weighing the evidence, the Panel took into account that the three human studies from which conclusions could be drawn for the scientific substantiation of the claim did not show an effect of L-theanine on improvement of cognitive function.On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of L-theanine from Camellia Sinensis (L.) Kuntze (tea) and improvement of cognitive function. Alleviation of psychological stressThe claimed effects are "relaxation" and "neurological functions". The target population is assumed to be the general population. In the context of the proposed wordings, clarifications from Member States and references provided, the Panel assumes that the claimed effects refer to alleviation of psychological stress. The Panel considers that alleviation of psychological stress might be a beneficial physiological effect.No references were provided from which conclusions could be drawn for the scientific substantiation of the claim.On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of L-theanine from Camellia Sinensis (L.) Kuntze (tea) and alleviation of psychological stress. Maintenance of normal sleepThe claimed effects are "mental and cognitive ...

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Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project

Abstract: A higher consumption of green tea is associated with a lower prevalence of cognitive impairment in humans.

Cited by 367 publications

References 32 publications

Green tea and coffee consumption is inversely associated with depressive symptoms in a Japanese working population

Green tea and coffee consumption is inversely associated with depressive symptoms in a Japanese working population

Neural effects of green tea extract on dorsolateral prefrontal cortex

Scientific Opinion on the substantiation of health claims related to L-theanine from Camellia sinensis (L.) Kuntze (tea) and improvement of cognitive function (ID 1104, 1222, 1600, 1601, 1707, 1935, 2004, 2005), alleviation of psychological stress (ID 159

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