Green-Synthesized Mosquito Oviposition Attractants and Ovicides: Towards a Nanoparticle-Based “Lure and Kill” Approach?

Abstract

Mosquitoes are key vectors of malaria, dengue, yellow fever, chikungunya, West Nile, Japanese encephalitis, lymphatic filariasis, Zika virus and St. Louis encephalitis virus. Eco-friendly control tools of Culicidae vectors are a priority. Green nanotechnologies may help to boost the effectiveness of mosquito vector control. We proposed a facile fabrication of poly-disperse and stable silver nanoparticles (AgNPs) using the Aganosma cymosa leaf extract. Nanoparticles were characterized by UV-visible spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction analysis, atomic force microscopy, scanning electron microscopy and transmission electron microscopy. Nanoparticles showed high toxicity on eggs and larvae of Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus. LC 50 values were 12.45, 13.58 and 14.79 lg/mL, respectively. No egg hatchability was noted post-treatment with 40, 50 and 60 lg/mL, respectively. Nanoparticles were found safer to non-target mosquito predators Anisops bouvieri, Diplonychus indicus and Gambusia affinis, LC 50 values ranged from 673.36 to 2247.43 lg/mL. Notably, AgNPs showed high oviposition attractiveness towards the three mosquito species. Overall, the oviposition attractiveness of the A. cymosa extract coupled with the ovicidal action of AgNPs can help to develop ''lure and kill'' tools to be used at mosquito breeding sites.

Promising nanomaterials in the fight against malaria

“…This has been observed for AgNPs synthesized from a plant that provides capping with metabolites that are attractive for a kind of mosquito. 135 In addition to Ag, other metal compositions including Au, Pd, Co, Ni, Cu and also ZnO and TiO 2 have shown toxicity against the mosquito larval stage, features that could be conveniently exploited to prevent malaria. 11 The utilization of noble metal-based NPs as antimalarial agents has been less described.…”

Nanolarvicidal Effect of Green Synthesized Ag-Co Bimetallic Nanoparticles on <i>Culex quinquefasciatus</i> Mosquito

“…[7], Streptomyces sp. [8], Aganosma cymosa leaf extract [9], bud extract of Polianthus tuberose [4], bark extract of Terminalia arjuna [[5], petal extracts of Tagetes sp. and Rosa sp.…”

Entomofaunal survey and larvicidal activity of greener silver nanoparticles: A perspective for novel eco-friendly mosquito control

“…They are transmitting many dreadful vector-borne diseases (VBDs) to public as the results causing millions of mortality and morbidity has been occurring every year ( Govindarajan et al, 2005 , Govindarajan et al, 2013 , WHO., 2016a , WHO, 2016 , WHO, 2018 , WHO, 2019 , Govindarajan et al, 2016a , Benelli et al, 2017a ). The VBDs are mainly transmitted by four genera of Aedes, Anopheles, Culex, and Mansonia of mosquitoes ( Sivakumar et al, 2011 , Benelli, 2015 , Benelli and Govindarajan, 2017 , Benelli et al, 2018 ). Recently, VBDs are very challenging problems and gives social-economic crisis in worldwide ( Krishnappa et al, 2012a , Govindarajan and Rajeswary, 2015 , Govindarajan et al, 2016b , Benelli et al, 2017b , Rekha et al, 2019 ).…”