Green synthesis of silver nanoparticles aimed at improving theranostics

Vedelago, José; Gómez, Cesar Gerardo; Valente, M.; Mattea, Facundo

doi:10.1016/j.radphyschem.2018.01.001

Cited by 26 publications

(5 citation statements)

References 25 publications

(27 reference statements)

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“…At the moment, the combination of therapy and diagnosis, known as theranostics, represents the most important, attractive, and challenging approach embraced by healthcare practitioners and researchers with respect to the effective and personalized therapy of cancer desideratum [ 219 ]. AgNPs are also plasmonic structures, capable of particularly scattering and absorbing the light impinging certain areas.…”

Section: Silver Nanoparticles For Other Medical Applicationsmentioning

confidence: 99%

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

et al. 2018

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During the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applications. Among modern biomedical potential of AgNPs, tremendous interest is oriented toward the therapeutically enhanced personalized healthcare practice. AgNPs proved to have genuine features and impressive potential for the development of novel antimicrobial agents, drug-delivery formulations, detection and diagnosis platforms, biomaterial and medical device coatings, tissue restoration and regeneration materials, complex healthcare condition strategies, and performance-enhanced therapeutic alternatives. Given the impressive biomedical-related potential applications of AgNPs, impressive efforts were undertaken on understanding the intricate mechanisms of their biological interactions and possible toxic effects. Within this review, we focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based nanostructures.

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Section: Silver Nanoparticles For Other Medical Applicationsmentioning

confidence: 99%

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

et al. 2018

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“…With regard to silver nanoparticles (AgNPs), similar to AuNPs, they can be used for dose enhancement in radiation therapy, but, unlike gold, they have shown antitumor activity. The synthesis of AgNPs is more versatile than AuNPs and they can even be synthesized by the reduction of silver nitrate with the amine groups of the gelatin matrix, which is already part of most of PGDs [ 151 ]. Vedelago et al [ 152 ] reported the dose enhancement produced by the presence of AgNPs in Fricke gel dosimeters by measuring the difference in the absorbance of dosimeters irradiated above and below the silver K-edge.…”

Section: Chemical and Physical Interactions Present In Gel Dosimetrymentioning

confidence: 99%

Chemical Overview of Gel Dosimetry Systems: A Comprehensive Review

Macchione

Páez

Strumia

et al. 2022

Gels

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Advances in radiotherapy technology during the last 25 years have significantly improved both dose conformation to tumors and the preservation of healthy tissues, achieving almost real-time feedback by means of high-precision treatments and theranostics. Owing to this, developing high-performance systems capable of coping with the challenging requirements of modern ionizing radiation is a key issue to overcome the limitations of traditional dosimeters. In this regard, a deep understanding of the physicochemical basis of gel dosimetry, as one of the most promising tools for the evaluation of 3D high-spatial-resolution dose distributions, represents the starting point for developing new and innovative systems. This review aims to contribute thorough descriptions of the chemical processes and interactions that condition gel dosimetry outputs, often phenomenologically addressed, and particularly formulations reported since 2017.

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“…Optimization of the drug encapsulation process and high duplicability at considerably lower cost are important factors that impact the amalgamation of theranostic nanomedicine in the clinical field (Madamsetty et al, 2019). Green synthesized nanomaterials are also being studied in the field of gel dosimetry for radiotherapy, but there is still a broad field of study yet to be unraveled and explored (Vedelago et al, 2018). In recent years, much encouraging evidence has sprouted that ensures a positive outlook for bio-inspired and green synthesized theranostic nanoparticles and their clinical applications in not an only cancer treatment, but a wide range of biomedical applications (Madamsetty et al, 2019).…”

Section: Applications Of Green Synthesized Silver Nanoparticles In Dr...mentioning

confidence: 99%

Anticancer Potential of Biosynthesized Silver Nanoparticles: A Review

Walimbe¹,

Dhawal²,

Kakodkar³

2022

EJBIO

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The field of nanotechnology has emerged as a promising course of study branching out into various biomedical fields such as therapeutics, imaging, and diagnostics. Metallic nanoparticles, specifically silver, are an important area of study due to their multifunctionality and diverse morphological characteristics. Amongst the various methods of synthesis of these multifunctional nanoparticles such as physical methods and chemical, green synthesis is the most suitable method due to its eco-friendly nature, cost-effectiveness, and ease of production. This article summarizes the broad spectrum of applications of green silver nanoparticles in the fields of cancer theranostics, imaging and diagnosis, and drug delivery. Bimetallic nanoparticles with silver as one of its major constituents are also explored to get a clear insight into the numerous prospective developments in the respective field.

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Green synthesis of silver nanoparticles aimed at improving theranostics

Cited by 26 publications

References 25 publications

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

Chemical Overview of Gel Dosimetry Systems: A Comprehensive Review

Anticancer Potential of Biosynthesized Silver Nanoparticles: A Review

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