Green synthesis of magnesium oxide nanoparticles and its applications: A review

Abinaya, S.; Kavitha, Helen P.; Prakash, Muthuramalingam; Muthukrishnaraj, A.

doi:10.1016/j.scp.2020.100368

Cited by 118 publications

(68 citation statements)

References 104 publications

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“…Plant phytochemicals may play a dual role by acting as both reducing and stabilizing agents in NPs synthesis. Additionally, the presence of bioactive molecules endows NPs with appellative functional properties [ 28 , 29 ]. Green-synthesized MgO NPs have been reported in several studies and applications [ 29 ], but this is not the case of Mg(OH) 2 NPs.…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, the presence of bioactive molecules endows NPs with appellative functional properties [ 28 , 29 ]. Green-synthesized MgO NPs have been reported in several studies and applications [ 29 ], but this is not the case of Mg(OH) 2 NPs. In addition, the bone application potential of these NPs has received little attention, compared with that of MgO NPs.…”

Section: Introductionmentioning

confidence: 99%

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Rosehip Extract-Functionalized Magnesium Hydroxide Nanoparticles and Its Effect on Osteoblastic and Osteoclastic Cells

et al. 2021

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Considering the role of magnesium in bone metabolism and the increasing relevance of plant-mediated green-synthesis, this work compares the bone cytocompatibility of magnesium hydroxide nanoparticles (NPs) produced by using pure water, Mg(OH)2, or a rosehip (RH) aqueous extract, Mg(OH)2RH. The NPs were evaluated for dose- and time-dependent effects on human osteoblastic and osteoclastic response, due to the direct involvement of the two cell types in bone metabolism. Mg(OH)2 NPs presented nanoplatelet-like morphology (mean diameter ~90 nm) and a crystalline structure (XRD analysis); the RH-mediated synthesis yielded smaller rounded particles (mean diameter <10 nm) with decreased crystallinity. On the ATR–FTIR spectra, both NPs presented the characteristic Mg-OH peaks; Mg(OH)2RH exhibited additional vibration bands associated with the presence of phytochemicals. On osteoblastic cells, NPs did not affect cell growth and morphology but significantly increased alkaline phosphatase (ALP) activity; on osteoclastic cells, particles had little effect in protein content, tartrate-resistant acid phosphatase (TRAP) activity, percentage of multinucleated cells, and cell area. However, compared with Mg(OH)2, Mg(OH)2RH increased osteoblastic differentiation by inducing ALP activity and promoting the expression of Runx2, SP7, Col1a1, and ALP, and had a negative effect on the expression of the osteoclastic genes NFATC1, CA2, and CTSK. These observations suggest the potential usefulness of Mg(OH)2RH NPs in bone regeneration.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Rosehip Extract-Functionalized Magnesium Hydroxide Nanoparticles and Its Effect on Osteoblastic and Osteoclastic Cells

et al. 2021

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“…Due to the characteristic structures and versatile properties of MgO nanoparticles, they displayed exceptional optical, electronic, magnetic, thermal, mechanical and chemical features. Therefore, MgO nanoparticles have significantly been utilized in catalysis, toxic wastes remediation and refractory material industries [ 5 , 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Highly Functionalized Modified Metal Oxides Polymeric Sensors for Potentiometric Determination of Letrozole in Commercial Oral Tablets and Biosamples

Shawky

El‐Tohamy

2021

Polymers

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The advanced and high-functional activities of magnesium oxide and copper oxide nanoparticles encourage the extensive use of these metal oxides as remarkable electroactive materials in electrochemical and sensing detections. The current study described a comparative sensing activity and selectivity of modified coated wire membrane sensors enriched with magnesium oxide and copper oxide nanoparticles for quantifying the breast cancer medication letrozole (LTZ) in its pharmaceutical form and human plasma. The fabricated sensors were based on the incorporation of LTZ with phosphomolybdic acid (PMA) to form the electroactive complex letrozole-phosphomolybate (LTZ-PM) in the presence of o-nitrophenyloctyl ether (o-NPOE) as a solvent mediator. Under optimum conditions, the modified sensors LTZ-PM-MgONPs and LTZ-PM-CuONPs demonstrated linear relationships of 1.0 × 10−8–1.0 × 10−2 and 1.0 × 10−10–1.0 × 10−2 mol L−1, respectively. Least square equations were calculated as EmV = (56.4 ± 0.7) log [LTZ] + 569.6 and EmV = (58.7 ± 0.3) log [LTZ] + 692.6 for LTZ-PM-MgONPs and LTZ-PM-CuONPs, respectively. The conventional type LTZ-PM showed a potential response EmV = (53.3 ± 0.5) log [LTZ] + 451.4 over concentration range of 1.0 × 10−6–1.0 × 10−2 mol L−1. The suggested sensors were successfully used to determine LTZ in pharmaceutical formulations and biosamples. Method validation ensured the suitability of the suggested potentiometric sensors.

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“…The positive sides may include promoting crop production and the nano-remediation of soils and water, whereas the main negative impacts may include the toxicity and nano-pollution ( Martínez et al, 2021 , Rizwan et al, 2021 ). The green synthesis of nanoparticles (NPs) could be achieved using plant extracts (i.e., leaves, roots, flowers and seeds), microbes (e.g., bacteria, yeast, fungi and algae) and biomolecules (enzymes, proteins, and carbohydrates), which represent biological substrates instead of chemical as solvents and stabilizing agents to reduce the harmful nature of the product ( Bandeira et al, 2020 , Abinaya et al, 2021 ). The biogenic synthesis of nanoparticles is “a boon” to human health, more convenient, economical and environmentally-friendly process compared to physical and chemical methods ( Stephen et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

“…The biogenic synthesis of nanoparticles is “a boon” to human health, more convenient, economical and environmentally-friendly process compared to physical and chemical methods ( Stephen et al, 2021 ). Many studies reported about the green synthesis of nanoparticles using plant extracts such as production of S-NPs using leaves of Ocimum basilicum ( Ragab and Saad-Allah, 2020 ), iron-NPs by green tea and black tea leaves ( Mareedu et al, 2021 ), Copper-NPs from Eucalyptus globulus and mint leaves ( Iliger et al, 2021 ), zinc oxide -NPs from Nilgiriantusciliantus leaf ( Resmi et al, 2021 ), nickel oxide-NPs from fennel ( Nigella sativa ) seeds ( Boudiaf et al, 2021 ) and magnesium oxide-NPs from different plant extracts ( Abinaya et al, 2021 ). These nano-nutrients also can support the struggle of humanity against many diseases particularly COVID-19 like nano-selenium ( He et al, 2021 ), and ZnO-NPs ( Gatadi et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Nano-biofortification of different crops to immune against COVID-19: A review

El-Ramady

Abdalla

Elbasiouny

et al. 2021

Ecotoxicology and Environmental Safety

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Human health and its improvement are the main target of several studies related to medical, agricultural and industrial sciences. The human health is the primary conclusion of many studies. The improving of human health may include supplying the people with enough and safe nutrients against malnutrition to fight against multiple diseases like COVID-19. Biofortification is a process by which the edible plants can be enriched with essential nutrients for human health against malnutrition. After the great success of biofortification approach in the human struggle against malnutrition, a new biotechnological tool in enriching the crops with essential nutrients in the form of nanoparticles to supplement human diet with balanced diet is called nano-biofortification. Nano biofortification can be achieved by applying the nano particles of essential nutrients (e.g., Cu, Fe, Se and Zn) foliar or their nano-fertilizers in soils or waters. Not all essential nutrients for human nutrition can be biofortified in the nano-form using all edible plants but there are several obstacles prevent this approach. These stumbling blocks are increased due to COVID-19 and its problems including the global trade, global breakdown between countries, and global crisis of food production. The main target of this review was to evaluate the nano-biofortification process and its using against malnutrition as a new approach in the era of COVID-19. This review also opens many questions, which are needed to be answered like is nano-biofortification a promising solution against malnutrition? Is COVID-19 will increase the global crisis of malnutrition? What is the best method of applied nano-nutrients to achieve nano-biofortification? What are the challenges of nano-biofortification during and post of the COVID-19?

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Green synthesis of magnesium oxide nanoparticles and its applications: A review

Cited by 118 publications

References 104 publications

Rosehip Extract-Functionalized Magnesium Hydroxide Nanoparticles and Its Effect on Osteoblastic and Osteoclastic Cells

Rosehip Extract-Functionalized Magnesium Hydroxide Nanoparticles and Its Effect on Osteoblastic and Osteoclastic Cells

Highly Functionalized Modified Metal Oxides Polymeric Sensors for Potentiometric Determination of Letrozole in Commercial Oral Tablets and Biosamples

Nano-biofortification of different crops to immune against COVID-19: A review

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