Green synthesis of biocompatible core–shell (Au–Ag) and hybrid (Au–ZnO and Ag–ZnO) bimetallic nanoparticles and evaluation of their potential antibacterial, antidiabetic, antiglycation and anticancer activities

Abstract

Graphical demonstartion of the Manikara zapota-mediated biosynthesis of Bimetallic nanoparticles (BNPs) and evalution of their biological activities.

Burdock-Derived Composites Based on Biogenic Gold, Silver Chloride and Zinc Oxide Particles as Green Multifunctional Platforms for Biomedical Applications and Environmental Protection

“…Moreover, minor peaks of Au and AgCl and major peaks of ZnO were observed in the XRD patterns for bi- and trimetallic particles. This behavior in the XRD pattern was also observed for Ag–ZnO NPs and Au–ZnONPs obtained from Manilkara zapota leaf extract [ 30 ], as well as for the Ag–ZnO NPs prepared from Silybum marianum [ 54 ].…”

“…The involvement of carboxylic acids, flavonoids, alcohols, and polyphenols in the bioreduction as well as the capping of bimetallic Ag-ZnO and Au-ZnO particles was also demonstrated via FTIR analysis by Anjum et al [ 30 ] who used Manilkara zapota leaf extract as a precursor. This fact underlines the role of phytochemicals in the donation of electrons or hydrogen atoms for the bioreduction of metals, and in the stabilization of resulting metallic nanoparticles, granting them at the same time a high biocompatibility and superior biological activity [ 30 ].…”

“…Anjum et al reported, for the first time, the synthesis of hybrid bicomponent nanoparticles (Au-AgNPs, AgNPs-ZnO, and AuNPs-AgNPs) using the same vegetal extract ( Manilkara zapota leaf extract). This extract has biocompatibility with human cells, and presents antitumoral, antidiabetic, antibacterial, and antiglycation activities and enhanced therapeutic activity as compared to their monometallic components [ 30 ].…”

Differential impact of biogenic and chemically synthesized zinc oxide nanoparticles on anti-aging, anti-oxidant and anti-cancerous activities: a mechanism based study

“…The experiment was performed thrice. The percentage of decolorization was calculated by following the method of Anjum et al 33…”

Advances in preparation and application of antibacterial hydrogels

“…The adverse consequences caused by the misuse of antibiotics have brought a severe challenge to the medical field [ 87 , 88 ], antibiotic-free treatment strategies have been actively developed [ 89 ]. In contrast to antibiotics, metal ions and metal oxides can enhance and maintain antibacterial activity, and biological extracts, as well as antibacterial polymers, have good antibacterial activity and biocompatibility [ 90 – 92 ]. In general, they can replace the use of antibiotics to reduce the incidence of drug abuse and resistance.…”