The present review highlights the various green method of synthesis and discrete applications of inner transition compounds. Green chemistry’s strategies are developing, producing, and using effective, reliable, and eco-friendly chemical products and processes to manage pollution. In this review, the greener or environmentally sound route for synthesizing lanthanide compounds is discussed briefly. The initial section briefs the fundamental principles of greener chemistry. It further emphasizes in-depth studies of synthesis of the different lanthanide-based complexes and their applications in different dimensions. It includes Green Synthesis of (a) lanthanide-doped nanophosphors, (b) rare-earth zirconates, (c) metal oxide nanoparticles, (d) rare-earth ions-doped nanocrystals-based photoluminescent materials, (e) self-assembled nanospherical dysprosium MOFs, and (f) nucleotide-based lanthanide coordination polymers. The last section dedicatedly reports the scope for the future perspective and recommendation in the novel area of research.