Green synthesis: an eco friendly approach for metallic nanoparticles synthesis

Kandav, Gurpreet; Sharma, Tamanna

doi:10.1080/02726351.2023.2281452

Cited by 5 publications

(1 citation statement)

References 198 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The biological method involves the utilization of plants, enzymes, and microbes such as bacteria, yeast, and fungi [23] to synthesize reliable, clean, simple, sustainable, cost-effective, and protein-capped nanoparticles with good dispersity. Among the biosystems, plants and microbes are specially considered as a potential source of biofunctional natural products, which is exploited by using them as reducing agents in the synthesis of different nanomaterials [24][25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Macrofungal Mediated Biosynthesis of Silver Nanoparticles and Evaluation of Its Antibacterial and Wound-Healing Efficacy

Vijayakumar,

Kim,

et al. 2024

IJMS

View full text Add to dashboard Cite

Recently, the utilization of biological agents in the green synthesis of nanoparticles has been given interest. In this study, silver nanoparticles were synthesized from an aqueous extract of macrofungus (mushroom), namely Phellinus adamantinus, in a dark room using 20 µL of silver nitrate. Biosynthesized silver nanoparticles were confirmed by analyzing them using a UV-Vis (ultraviolet-visible) spectrophotometer. The synthesized silver nanoparticles were optimized at different pH and temperatures with various dosages of AgNO3 (silver nitrate) and fungal extracts. The synthesized AgNPs (silver nanoparticles) were characterized using TEM (transmission electron microscopy) and EDX (energy-dispersive X-ray) analyses, which confirmed the presence of silver nanoparticles. The size of the nanosilver particles was found to be 50 nm with higher stability. The mycosynthesized AgNPs showed effective antibacterial activity against strains of Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (E. coli and Pseudomonas aeruginosa) bacteria. The minimum inhibitory concentration (MIC) was found to be 3.125 μg/mL by MIC assay. The MTT assay (3-[4,5-dimethylthiazol-2-yl] 2,5-diphenyl-2H-tetrazolium bromide) was performed to study cytotoxicity, and reduced cell viability was recorded at 100 μg/mL. Silver-Polygalacturonic acid-Polyvinyl alcohol ((Ag-PGA)-PVA) nanofiber was prepared using the electrospinning method. The in vitro wound scratch assay was demonstrated to study the wound-healing efficacy of the prepared nanofiber. The wound-healing efficacy of the AgNP-incorporated nanofiber was found to be 20% after 24 h. This study will lay a platform to establish a unique route to the development of a novel nanobiomaterial and its application in antibacterial and wound-healing therapy.

show abstract