Green Synthesis: A Novel Method for Bromination of 7-AminoPhthalide

Abstract

<div>A novel method for preparing a bromo substituted 7-Amino-phthalides and 7-</div><div>Amino-3-hydroxy-phthalides via the bromonium ion intermediate under acidic conditions at</div><div>higher temperature were developed. The results will illustrate the potential utility of this</div><div>method as an environment-friendly process for synthesis of bromo substituted aryl amines,</div><div>along with conservation of half mole equivalent of halides.</div>