Green Oxidation of Aromatic Hydrazide Derivatives Using an Oxoammonium Salt
Nidheesh Phadnis,
Jessica A. Molen,
Shannon M. Stephens
et al.
Abstract:Aromatic diazenes are often prepared by oxidation of the corresponding hydrazides using stoichiometric quantities of nonrecyclable oxidants. We developed a convenient alternative protocol for the oxidation of aromatic hydrazides using Bobbitt's salt (1), a metal-free, recyclable, and commercially available oxoammonium reagent. A variety of aryl hydrazides were oxidized within 75 min at room temperature using the developed protocol. Computational insight suggests that this oxidation occurs by a polar hydride tr… Show more
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