Green microextraction methodologies for sample preparations

Kokosa, John M.; Przyjazny, Andrzej

doi:10.1016/j.greeac.2022.100023

Cited by 36 publications

(11 citation statements)

References 222 publications

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“…The major compounds identified in the floral bouquet of dried flower were hexanal, Z-2-hexenal, 1-hexanol, eucalyptol, linalool, and camphor [ 43 ]. According to the Green Analytical Chemistry and Green Sample Preparation principles, SPME-GC-MS analysis procedure should be preferable compared to traditionally used essential oil extraction methods, such as steam- or hydrodistillation paired with GC-FID analysis [ 47 , 48 , 49 ]. The SPME-GC-MS analysis procedure is more sensitive, consumes less energy, involves no solvent use, and minimizes sample volume and waste production, but allows for a comparison of the composition of volatile compounds in different plant species [ 50 ].…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Screening and Antioxidant Activity of Selected Estonian Galium Species

et al. 2023

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The aim of the present study was to examine three different Galium species from the native population of Estonia, Galium verum, Galium aparine, and Galium mollugo, to characterise their non-volatile and volatile phytochemical composition and antioxidant activity. The main groups of bioactive compounds in the plants were quantified by colorimetric tests, showing high concentrations of polyphenols (up to 27.2 ± 1.5 mg GAE/g), flavonoids (up to 7.3 ± 0.5 mg QE/g) and iridoids (up to 40.8 ± 2.9 mg AE/g). The species were compared using HPLC-DAD-MS/MS, revealing some key differences in the phytochemical makeup of the extracts. The most abundant compound in the extracts of Galium verum blossoms and herb was found to be asperuloside, in Galium aparine herb, asperulosidic acid, and in Galium mollugo herb, chlorogenic acid. Additionally, the composition of volatile compounds was analysed by SPME-GC-MS. The degree of variability between the samples was high, but three volatiles, hexanal, anethole, and β-caryophyllene, were quantified (≥1%) in all analysed samples. The antioxidative activity of all extracts was evaluated using the ORACFL method, demonstrating that the Galium species from Estonia all exhibit strong antioxidant capacity (up to 9.3 ± 1.2 mg TE/g). Out of the extracts studied, Galium verum blossoms contained the highest amounts of bioactives and had the strongest antioxidant capacity.

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Section: Introductionmentioning

confidence: 99%

Phytochemical Screening and Antioxidant Activity of Selected Estonian Galium Species

et al. 2023

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“…Microextraction procedures can be categorized into solid phase-and liquid phasebased techniques [6,7]. Procedures based on solid-phase microextraction, involving adsorption or absorption of the compounds of interest onto a solid sorbent or film, can be divided in microextraction by packed sorbent (MEPS), solid-phase microextraction (SPME), micro solid-phase extraction (µ-SPE), dispersive solid-phase extraction (DSPE) or matrix solid-phase dispersion, magnetic solid-phase extraction (MSPE) and molecularly imprinted polymers (MIPs).…”

Section: Introductionmentioning

confidence: 99%

Solid Phase-Based Microextraction Techniques in Therapeutic Drug Monitoring

et al. 2023

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Therapeutic drug monitoring is an established practice for a small group of drugs, particularly those presenting narrow therapeutic windows, for which there is a direct relationship between concentration and pharmacological effects at the site of action. Drug concentrations in biological fluids are used, in addition to other clinical observation measures, to assess the patient’s status, since they are the support for therapy individualization and allow assessing adherence to therapy. Monitoring these drug classes is of great importance, as it minimizes the risk of medical interactions, as well as toxic effects. In addition, the quantification of these drugs through routine toxicological tests and the development of new monitoring methodologies are extremely relevant for public health and for the well-being of the patient, and it has implications in clinical and forensic situations. In this sense, the use of new extraction procedures that employ smaller volumes of sample and organic solvents, therefore considered miniaturized and green techniques, is of great interest in this field. From these, the use of fabric-phase extractions seems appealing. Noteworthy is the fact that SPME, which was the first of these miniaturized approaches to be used in the early ‘90s, is still the most used solventless procedure, providing solid and sound results. The main goal of this paper is to perform a critical review of sample preparation techniques based on solid-phase microextraction for drug detection in therapeutic monitoring situations.

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“…In response to these needs, novel microextraction-based methods have emerged. Microextraction involves using a small volume of an extracting phase compared to the sample volume [47][48][49][50]. While it may not achieve exhaustive extraction, it significantly increases the concentration of the analyte in the extractive phase, reducing solvent usage [47][48][49][50].…”

Section: Introductionmentioning

confidence: 99%

Innovative Solutions for Food Analysis: Microextraction Techniques in Lipid Peroxidation Product Detection

Custodio-Mendoza,

Ares-Fuentes,

Carro

2023

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Lipid peroxidation, the most aggressive reaction in food, results in the formation of reactive organic compounds that detrimentally impact food sensory qualities and consumers’ health. While controlled lipid peroxidation can enhance flavors and appearance in certain foods, secondary peroxidation products lead to sensory deterioration in a variety of products, such as oils, alcoholic beverages, and meat. This publication reviews the use of modern analytical techniques for detecting and quantifying carbonyl compounds, i.e., secondary lipid peroxidation products. The paper focuses specifically on microextraction-based methods: dispersive liquid-liquid microextraction (DLLME), solid-phase microextraction (SPME), and gas-diffusion microextraction (GDME). These techniques offer efficient and sensitive approaches to extracting and quantifying lipid oxidation products and contribute to the understanding of oxidative deterioration in various food products. The review outlines recent advancements, challenges, and limitations in these microextraction techniques, as well as emphasizes the potential for further innovation and improvement in the field of food analysis.

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Green microextraction methodologies for sample preparations

Cited by 36 publications

References 222 publications

Phytochemical Screening and Antioxidant Activity of Selected Estonian Galium Species

Phytochemical Screening and Antioxidant Activity of Selected Estonian Galium Species

Solid Phase-Based Microextraction Techniques in Therapeutic Drug Monitoring

Innovative Solutions for Food Analysis: Microextraction Techniques in Lipid Peroxidation Product Detection

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