“…Moreover, different polymorphs of a drug molecule can have completely different physiochemical properties such as solubility, permeability, stability, tablettability, hygroscopicity, and so on, properties that are crucial in pharmaceutical formulation development . Thus, screening for all the possible polymorphic forms of a drug and control of the polymorphic form of drug molecules is of considerable importance. − In recent years polymorph screening through mechanochemistry is becoming popular as a greener approach. , Furthermore, liquid-assisted grinding (LAG) is one of the frequently employed strategies for mechanochemical control over cocrystal, polymorphs, etc. − The stabilization of a specific polymorph of γ-aminobutyric acid by using the LAG technique with high-polarity solvents has been reported recently . Emmerling and co-workers demonstrated the formation of a metastable form III of benzamidine by using nicotinamide seeds in a LAG experiment with ethanol .…”