Green Extraction of Carotenoids from Fruit and Vegetable Byproducts: A Review

Kultys, Ewelina; Kurek, Marcin Andrzej

doi:10.3390/molecules27020518

Cited by 43 publications

(9 citation statements)

References 42 publications

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“…In conducting cytotoxicity assays, solvent compatibility is extremely important in cell culture systems, where cells are exposed to different test compound concentrations [77,78] . Numerous organic solvents, without toxic effects on cells, are widely used for dissolving the hydrophobic compounds in different types of cell culture assays [79–81] . Therefore, in a preliminary assay, it is important to determine the maximum or minimum tolerable concentration for solvent on cell toxicity that can be used to prepare solutions of herbal extracts or other compounds [82–85] .…”

Section: Methodsmentioning

confidence: 99%

Cytotoxic Activity of Herbal Medicines as Assessed in Vitro: A Review

Gavanji

Bakhtari

Famurewa

et al. 2023

Chemistry & Biodiversity

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Since time immemorial, human beings have sought natural medications for treatment of various diseases. Weighty evidence demonstrates the use of chemical methodologies for sensitive evaluation of cytotoxic potentials of herbal agents. However, due to the ubiquitous use of cytotoxicity methods, there is a need for providing updated guidance for the design and development of in vitro assessment. The aim of this review is to provide practical guidance on common cell-based assays for suitable assessment of cytotoxicity potential of herbal medicines and discussing their advantages and disadvantages Relevant articles in authentic databases, including PubMed, Web of Science, Science Direct, Scopus, Google Scholar and SID, from 1950 to 2022 were collected according to selection criteria of in vitro cytotoxicity assays and protocols. In addition, the link between cytotoxicity assay selection and different factors such as the drug solvent, concentration and exposure duration were discussed.

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Section: Methodsmentioning

confidence: 99%

Cytotoxic Activity of Herbal Medicines as Assessed in Vitro: A Review

Gavanji

Bakhtari

Famurewa

et al. 2023

Chemistry & Biodiversity

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“…Low yields of plant pigments have been previously described when using supercritical carbon dioxide extraction. For example, yields of around 1% were reported for Bixa orellana seeds after extraction at 200 bar and 40 °C [73] Kultys and Kurek [74] argued that the extraction of carotenoids using SFE produces low yields due to the high molecular weight of the extractable compounds. Nevertheless, the use of polar solvents, such as ethanol, increases the recovery of plant pigments.…”

Section: Plant Pigments Total Polyphenols and Antioxidant Activity Of...mentioning

confidence: 99%

Comparison of Four Oil Extraction Methods for Sinami Fruit (Oenocarpus mapora H. Karst): Evaluating Quality, Polyphenol Content and Antioxidant Activity

Muñoz

Casimiro-Gonzales

Gómez‐Coca

et al. 2022

Foods

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The sinami palm (Oenocarpus mapora H. Karst) is a plant from the South American Amazonia that has great potential for industrial applications in the development of functional foods, nutraceuticals and cosmeceuticals. In this manuscript, the physicochemical properties, total polyphenol content and antioxidant activity of sinami oil that was obtained using four extraction systems, namely expeller press extraction (EPE), cold press extraction (CPE), ultrasound-assisted extraction (UAE) and supercritical fluid extraction (SFE), were studied and compared. The oxidative stability (OSI) was statistically non-significant in EPE and SFE. The chromatic properties (CIELab) were influenced by the extraction methods and SFE presented high values of L* and a lower content of plant pigments. Ultrasound-assisted extraction showed a higher content of polyphenols and higher antioxidant activity. Different analyses for the evaluation of the physicochemical properties, the content of total polyphenols and antioxidant activity were used to classify sinami oil according to chemometrics using principal component analysis (PCA). For example, the sinami oil that was obtained using each extraction method was in a different part of the plot. In summary, sinami oil is an excellent resource for plant pigments. Additionally, the information that was obtained on the quality parameters in this study provided a good foundation for further studies on the characterization of major and minor compounds.

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“…Traditionally, mechanical processing or conventional extraction techniques using organic solvents have been employed to recover oil from plant seeds. However, microwave-assisted extraction (MAE) and supercritical fluid extraction (SFE) techniques have gained major importance in recent years, being a part of the green chemistry principles due to their reduced environmental impact combined with increased extraction yields and reduced extraction times and solvent consumption [ 13 , 14 , 15 ]. MAE is based on the ability of microwave irradiation to penetrate into certain materials and interact with polar components generating heat [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Valorization of Tomato Seed By-Products as a Source of Fatty Acids and Bioactive Compounds by Using Advanced Extraction Techniques

Solaberrieta

Mellinas

Espagnol

et al. 2022

Foods

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In this work, lipids and bioactive compounds from tomato seed by-products were extracted and compared by using advanced extraction techniques, such as microwave-assisted extraction (MAE) and supercritical fluid extraction (SFE). The influence of different extraction parameters, including extraction temperature (T), time (t) and solvent volume (V) for MAE as well as extraction temperature (T), pressure (P) and flow rate (F) for SFE-CO2, was evaluated on tomato seed oil (TSO) yield and fatty acids composition using response surface methodology (RSM). Optimum extraction conditions for MAE were 56.2 °C, 29.0 min, and 67.6 mL, whereas conditions of 60.2 °C, 400.0 bar, and 64.6 g min−1 were found for SFE-CO2. Under these conditions, higher TSO extraction yields were obtained by MAE compared to SFE-CO2 (25.3 wt% and 16.9 wt%, respectively), while similar fatty acids profiles were found by GC in terms of FAMEs composition: methyl palmitate, methyl stearate, methyl oleate, and methyl linoleate, accounting for around 80 wt% of unsaturated fatty acids. TSO MAE extracts showed high DPPH• radical scavenging activity which was related to the presence of tocopherols; in particular γ-tocopherol, which was found as the dominant homologue (260.3 ± 0.6 mg kgTS−1) followed by a lower amount of α-tocopherol (6.53 ± 0.12 mg kgTS−1) by HPLC-DAD. The obtained results suggested that tomato seeds are an interesting source of bioactive compounds with potential use in a wide range of nutritional and food applications, increasing the added value of this by-product, which is currently underexploited.

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Green Extraction of Carotenoids from Fruit and Vegetable Byproducts: A Review

Cited by 43 publications

References 42 publications

Cytotoxic Activity of Herbal Medicines as Assessed in Vitro: A Review

Cytotoxic Activity of Herbal Medicines as Assessed in Vitro: A Review

Comparison of Four Oil Extraction Methods for Sinami Fruit (Oenocarpus mapora H. Karst): Evaluating Quality, Polyphenol Content and Antioxidant Activity

Valorization of Tomato Seed By-Products as a Source of Fatty Acids and Bioactive Compounds by Using Advanced Extraction Techniques

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