Green Antibiotic Daun Sirih (Piper betle l.) Sebagai Pengganti Antibiotik Komersial untuk Penanganan Mastitis

Abstract

(Green antibiotic betel leaf (Piper betle l.) as a substitute for commercial antibiotic in mastitis treatment) ABSTRACT. The present study was carried out to investigate the possible antibacterial activity of betel leaf on the amount and microscopic appearance of mastitis-causing bacteria. The randomized block design with 5 treatment groups were : K group (mastitis milk only as negative control), Ab group (mastitis milk + antibiotic penicillin-dihydrostreptomycin as positive control), S1 group (mastitis milk + 1,25 ml betel leaf water extract), S2 group (mastitis milk+ 2,5 ml betel leaf water extract), and S3 group (mastitis milk + 5 ml betel leaf water extract). The result showed that the amount of bacteria in the betel leaves groups (S1, S2, and S3 groups) were lower (P 0,05) than that of the control group (K group). Nonetheless the different concentration of betel leaf water extract in the S1, S2 and S3 groups did not affect to the amount of bacteria (P 0,05). Moreover, this research showed that betel leaf water extract had the same effectiveness with commercial antibiotic penicillin-dihydrostreptomycin to inhibit the growth of bacteria as indicated by the same amount of bacteria (P0,05) among the betel leaf groups (S1, S2, and S3 groups) and the Ab group. Gram-positive and negative bacteria were seen in the K group. However, only Gram-negative bacteria were visible in the betel leaf groups (S1, S2, and S3 groups) and in the Ab groups, indicating that betel leaf had the same effectiveness as penicillin-dihydrostreptomycin to inhibit the growth of Gram-positive bacteria.

Ethnoveterinary study of medicinal plants used for cattle treatment in Bojonegoro District, East Java, Indonesia

“…Several cattle breeders also mentioned that the leaves of this plant are crucially effective for treating diarrhea and detoxification. This is similar to research by Lutviandhitarani et al (2015), which states that Piper betle L. leaves have good anti-oxidant and anti-bacterial activity because they contain phytochemichals such as eugenols, tannins, alkaloids, and terpenoids. The Javanese community believes that plants 4243 have good potential to heal wounds.…”

EFFECTIVENESS OF CHEWING MARSHMALLOW CONTAINING BETEL CHEW ON SALIVARY Streptococcus mutans IN 12 YEARS OLD CHILDREN OF SMPN 29 PALEMBANG

“…Ketiga bahan tersebut masing-masing memiliki kandungan zat antibakteri yaitu tanin dan minyak atsiri pada daun sirih, quersetin dan katekin pada gambir, dan kalsium hidroksida pada kapur sirih (Marshall, 2005). Berdasarkan kandungan zat antibakteri tersebut maka komponen kinang berpotensi untuk dapat dijadikan sebagai bahan antiseptic (Wahyono, 2015).…”

Pemberdayaan Masyarakat Dalam Pencegahan Demam Typhoid Dengan Pemanfaatan Antiseptik Jus Daun Sirih Hijau Sebagai Pencuci Buah Dan Sayur

“…Hal tersebut sesuai dengan teori yang dikemukakan oleh (Reveny, 2011) dan diperkuat juga oleh penelitian (Haryuni et al, 2017) bahwa jus daun sirih memiliki daya hambat yang sangat nyata terhadap pertumbuhan bakteri Salmonella typhi. (Lutviandhitarani et al, 2015) mengatakan bahwa pada daun sirih hijau mengandung zat katekol, piragol, quinon, eugol, flavon, dan flavonoid termasuk dalam golongan fenol dan mempunyai kemampuan sebagai anti mikroba. Selain itu, daun sirih juga mengandung minyak atsiri sampai 4,2%.…”