Green and Efficient Procedure for Suzuki–Miyaura and Mizoroki–Heck Coupling Reactions Using Palladium Catalyst Supported on Phosphine Functionalized ZrO2 NPs (ZrO2@ECP-Pd) as a New Reusable Nanocatalyst

Abstract

In this article, palladium supported on phosphine functionalized ZrO 2 NPs (ZrO 2 @ECP-Pd) has been introduced as a novel and efficient nanocatalyst for SuzukiMiyaura and MizorokiHeck reactions. This new catalyst was prepared from the reaction of Pd(OAc) 2 and PPh 2 -functionalized ZrO 2 NPs, and then characterized using FT-IR, XRD, SEM, TEM, TGA and ICP techniques. The above experimental results showed that the synthesized catalyst existed as spheres with a mean size range of 1040 nm. The prepared ZrO 2 @ECP-Pd nanocatalyst was shown to be highly efficient in the Suzuki Miyaura and MizorokiHeck cross-coupling reactions of a wide range of aryl halides including electron-rich and electronpoor aryl iodides/bromides, and heteroaryl iodides, affording the corresponding products in good to excellent yields in short reaction times. The notable feature of the present protocol is the use of water and [bmim]PF 6 as environmentally benign solvents, which eliminate the need of toxic solvent. In addition to the aforementioned favorable properties, the nanocatalyst can be recovered and reused for the subsequent reactions (at least six times) without any appreciable loss of efficiency.

An Eco-Friendly Method for Voltametric Determination of Prucalopride Succinate on simple nanoparticles Modified Carbon Paste Electrode

“…This is mainly due to the unique characteristics of NPs and the novelty they introduce in such applications The main functions of metal nanoparticles in electroanalysis include increasing the surface area of the electrode leading to an increase the electroactive species loading on it, in addition, they have good catalytic activities as they function as ultra -microelectrode clusters for large amount substrate catalysis and they catalyse the deposition of reactive species 19 . Among the transition metal oxide nanoparticles, zirconium oxide nanoparticles (ZrO2 NPs) have attracted major research interest due to its unique thermal, catalytic, electrical, sensing, optical, mechanical, and biocompatible characters [20][21][22] .…”

CuII Anchored onto the Magnetic Talc: A New Magnetic Nanostructured Catalyst for the One‐Pot Gram‐Scale Synthesis of 1H‐Pyrazolo[1,2‐b]phthalazine‐5,10‐dione Derivatives

“…In continuation of our studies on the synthesis and application of magnetic nanostructured catalysts and to develop a new synthetic methodology for the preparation of 1 H ‐pyrazolo[1,2‐b]phthalazine‐5,10‐diones via one‐pot multicomponent reactions (MCRs), Cu II anchored onto the magnetic talc (γ‐Fe 2 O 3 / talc/Cu II NPs) as a magnetically heterogeneous nanocatalyst from commercially available chemicals in multiple steps was prepared. (Scheme ) The method consists of the reaction between a mixed salt‐solution of ferrous and ferric ions and NaOH in the presence of talc powder ( I ) as promising supporting material for catalysts in organic reactions.…”