Green and efficient delivery of pesticides throughout their life cycle via cooperative solid and solution self-assembly

Structural Elucidation and Release Enhancement of the Florfenicol/β-Cyclodextrin Inclusion Complex

“…To further elucidate the mechanism underlying the release of FLO and FLO/β-CD inclusion complex, the release kinetics was investigated employing the following four kinetics models: zero-order, first-order, Higuchi, and Ritger–Peppas models, as represented in eqs –, respectively M t M ∞ = italickt + b M t M ∞ = 1 − e − italickt M t M ∞ = k t 1 / 2 + b M t M ∞ = k t n where M t refers to the release amount (mg) at time t , M ∞ refers to the release amount (mg) at infinite time, t refers to the time (min), k is the kinetic constant, and n is the diffusion parameter.…”

“…This process fixed the positions of C and O atoms, focusing optimization on H atoms. Molecular electrostatic potential surface (MEPS) evaluations and independent gradient model based on Hirshfeld partition (IGMH) analysis were then carried out using Multiwfn 3.8, based on DFT-derived wave functions. , The results were visualized using Visual Molecular Dynamics (VMD) 1.9.3.…”

“…To further elucidate the mechanism underlying the release of FLO and FLO/β-CD inclusion complex, the release kinetics was investigated employing the following four kinetics models: zeroorder, first-order, Higuchi, and Ritger−Peppas models, as represented in eqs 2−5, respectively. 39…”