Greater increases in cocaine cue-induced craving and pupillary size in cocaine addicts endorsing cocaine-induced paranoia

Rosse, Richard B.; Alim, Tanya N.; Vocci, Frank; Hess, Anemarie L.; Johri, Surendra K.; Deutsch, Steven

doi:10.1016/0006-3223(94)90939-3

Cited by 2 publications

(3 citation statements)

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“…A low body mass index (BMI) could increase the risk for cocaine-induced psychosis in crack users, and a high BMI could be a protective factor. 41 Gender. The results have been inconsistent regarding the influence of gender on the risk of developing cocaine-induced psychosis.…”

Section: Risk Factors For Cocaine-induced Psychosismentioning

confidence: 99%

An International Perspective and Review of Cocaine-Induced Psychosis: A Call to Action

et al. 2014

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Cocaine use can induce transient psychotic symptoms that include suspiciousness, paranoia, hallucinations, and other cocaine-related behaviors. In this commentary, the authors provide an international perspective while reviewing the recent advances in epidemiology, clinical features, and risk factors related to cocaine-induced psychosis exhibited by patients with cocaine use disorders. In some settings, the occurrence of cocaine-induced psychosis has been shown to be as high as 86.5%. Many risk factors have been linked with cocaine-induced psychosis, including the quantity of cocaine consumed, lifetime amount of cocaine use, onset of cocaine dependence, years of use, routes of administration, other substance use disorder comorbidity, weight, gender, comorbidity with other medical and mental health disorders, genetics, and pharmacological interactions. Research has shown that the evaluation of cocaine-induced psychosis in patients with cocaine use is clinically relevant, especially in those patients who consume high amounts of cocaine, have a cannabis dependence history, have antisocial personality disorder, use administration routes other than intranasal, or exhibit attention-deficit/hyperactivity disorder (ADHD) comorbidity. Currently, the literature lacks information regarding the evolution of cocaine dependence or cocaine-dependent patients' risk for developing schizophrenia or other psychotic disorders. Furthermore, clinicians still do not have an evidence-based pharmacological approach to management of cocaine dependence available to them. Additional research is also needed regarding risk factors such as neurobiological markers and personality traits. Finally, we recommend the development of an integrative model including all of the risk factors and protective factors for cocaine-induced psychosis.

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Section: Risk Factors For Cocaine-induced Psychosismentioning

confidence: 99%

An International Perspective and Review of Cocaine-Induced Psychosis: A Call to Action

et al. 2014

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“…Thus, nicotine use may ultimately influence drug-seeking behavior. Although a relationship between increased drug-seeking behavior and psychotic symptoms has been observed clinically (Rosse et al 1994), the mechanism of this relationship is unknown. It has been observed, however, than sensitization to stimulants is common in both chronic stimulant abuse and in endogenous psychoses (Yui et al 1999).…”

Section: Abmentioning

confidence: 99%

“…For most cocaine addicts, symptoms abate significantly within the first day or two of detoxification, but there is also evidence of more persistent symptomatology, particularly paranoia (Manschreck et al 1988). These psychotic symptoms are associated with increased craving and diminished likelihood of abstinence (Rosse et al 1994;Williamson et al 1997). Attempts to treat stimulant addicts with neuroleptic drugs for more extended periods of time generally have not been successful because of patients' extreme resistance to taking the medication (Gawin et al 1989).…”

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confidence: 99%

Reversal of Diminished Inhibitory Sensory Gating in Cocaine Addicts by a Nicotinic Cholinergic Mechanism

Adler

Olincy

Cawthra

et al. 2001

Neuropsychopharmacology

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Greater increases in cocaine cue-induced craving and pupillary size in cocaine addicts endorsing cocaine-induced paranoia

Cited by 2 publications

References 0 publications

An International Perspective and Review of Cocaine-Induced Psychosis: A Call to Action

An International Perspective and Review of Cocaine-Induced Psychosis: A Call to Action

Reversal of Diminished Inhibitory Sensory Gating in Cocaine Addicts by a Nicotinic Cholinergic Mechanism

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