Greater Dietary Inflammatory Potential Is Associated With Higher Likelihood of Abdominal Aortic Calcification

Zheng, Qin; Chang, Kaixi; Liao, Ri-Qiang; Jiang, Luojia; Yang, Qinbo; Su, Baihai

doi:10.3389/fcvm.2021.720834

Cited by 14 publications

(9 citation statements)

References 69 publications

(70 reference statements)

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“…Food parameters can increase or decrease inflammatory potential through pro-inflammatory and anti-inflammatory markers; according to the influence of food parameters on inflammation, significantly increase IL-1β, IL-6, TNF-α or CRP, or decrease IL-4 or IL-10 Give "+1", it is a proinflammatory effect; significantly reduce IL-1β, IL-6, TNF-α or CRP, or increase the "-1" given by IL-4 or IL-10, which is an anti-inflammatory effect; if food If the parameter does not produce any significant changes in inflammation markers, "0" is assigned. [64][65][66]…”

Section: Dietary Inflammatory Index (Dii) Overview Of DIImentioning

confidence: 99%

Association of Dietary Inflammatory Index (DII) and Depressive Disorders

Li¹,

Zhan²,

Huang³

et al. 2021

JIR

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A lot of evidence shows that inflammation is related to the development of depression. However, the heterogeneity of depression hinders efforts to understand, prevent and treat this disease. The purpose of this comprehensive review is to summarize the links between inflammation and the established core features of depression, which show more homogeneity than the syndrome itself: overreaction to negative information, changes in reward processing, and cognitive control decline, and somatic syndrome. For each core feature, we first briefly outline its relevance to depression and neurobiological basis, and then review the evidence to investigate the potential role of inflammation. We mainly focus on the discovery of the experimental paradigm of exogenous inflammation. We concluded that inflammation may play a role in overreaction to negative information, altered reward responses, and physical symptoms. There is less evidence to support the effect of inflammation on cognitive control by standard neuropsychological measures. Finally, we discussed the implications for future research and recommendations on how to test the role of inflammation in the pathogenesis of heterogeneous mental illness.

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Section: Dietary Inflammatory Index (Dii) Overview Of DIImentioning

confidence: 99%

Association of Dietary Inflammatory Index (DII) and Depressive Disorders

Li¹,

Zhan²,

Huang³

et al. 2021

JIR

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“…Among the general population aged 45–75 years old, the prevalence of thoracic aortic calcification and coronary artery calcification has reached 63.1 and 46.7%, respectively [ 2 ]. Vascular calcification has a strong correlation with ageing, chronic kidney disease, diabetes, hypertension and smoking [ 3 , 4 ]. It can induce vascular compliance decrease, arterial wall thickening, luminal stenosis, plaque instability and plaque rupture [ 5 ], which may result in a series of cardiovascular diseases as well as adverse cardiovascular and cerebrovascular events [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Beneficial effect of the short-chain fatty acid propionate on vascular calcification through intestinal microbiota remodelling

et al. 2022

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Background Vascular calcification is a major cause of the high morbidity and mortality of cardiovascular diseases and is closely associated with the intestinal microbiota. Short-chain fatty acids (SCFAs) are derived from the intestinal microbiota and can also regulate intestinal microbiota homeostasis. However, it remains unclear whether exogenous supplementation with propionate, a SCFA, can ameliorate vascular calcification by regulating the intestinal microbiota. This study was conducted to explore the roles of propionate and the intestinal microbiota in the process of vascular calcification. Methods In total, 92 patients were enrolled consecutively as the observational cohort to analyse the relationship between SCFAs and vascular calcification in both blood and faecal samples. A rat model of vascular calcification was induced by vitamin D3 and nicotine (VDN) to validate the effect of propionate. Differences in the intestinal microbiota were analysed by 16S ribosomal RNA gene sequencing. Faecal microbiota transplantation and Akkermansia muciniphila transplantation experiments were performed to evaluate the functions of the intestinal microbiota. Results The results of the observational cohort study revealed that the levels of SCFAs (particularly propionate) in both blood and faecal samples independently correlated negatively with calcification scores (P < 0.01). To verify the activities of propionate, it was provided to VDN-treated rats, and oral or rectal propionate delivery reshaped the intestinal microbiota, resulted in elevated SCFA production, improved intestinal barrier function and alleviated inflammation, ultimately ameliorating vascular calcification. Furthermore, we demonstrated that transplantation of the propionate-modulated intestinal microbiota induced beneficial outcomes similar to those with oral or rectal propionate administration. Interestingly, linear discriminant analysis (LDA) effect size (LEfSe) revealed that oral or rectal propionate administration and propionate-modulated intestinal microbiota transplantation both enriched primarily Akkermansia. Subsequently, we demonstrated that Akkermansia supplementation could ameliorate VDN-induced vascular calcification in rats. Conclusions Propionate can significantly ameliorate vascular calcification in VDN-treated rats, and this effect is mediated by intestinal microbiota remodelling. The findings in our study indicate that the intestinal tract-vessel axis is a promising target for alleviating vascular calcification.

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“…Our study focused on the association of adherence to DGA with AAC, more appropriate to the national context, compared with regional dietary patterns or custom dietary patterns. Furthermore, the abdominal aorta is prone to calcification ( 36 ) and attention to its calcification can be beneficial for earlier prevention. Thus, this was the first study concentrating on the relationship of HEI-2015 with AAC.…”

Section: Discussionmentioning

confidence: 99%

Association between healthy eating index-2015 and abdominal aortic calcification among US Adults

Jia

Zhang

et al. 2023

Front. Nutr.

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AimsTo evaluate the relationship of the healthy eating index-2015 (HEI-2015) with abdominal aortic calcification (AAC) in US adults.MethodsWe conducted a cross-sectional study with data extracted from the National Health and Nutrition Examination Survey (NHANES). AAC score was measured using the scoring system of Kauppila (AAC-24) and Schousboe (AAC-8). HEI-2015, which was used for evaluating compliance with Dietary Guidelines for Americans (DGA), was calculated through two rounds of 24-h recall interviews. HEI-2015 was categorized as inadequate (<50), average (50~70), and optimal (≥70) groups for analysis, while the AAC-24 score was grouped by whether the score was >0. Weighted multiple regression analyses were conducted to estimate the association of HEI-2015 with AAC score and the presence of AAC. Moreover, smooth curve fittings, based on a generalized additive model (GAM), were applied to evaluate a possible non-linear relationship. Sensitivity analysis and subgroup analysis were performed to provide more supporting information.ResultsA total of 2,704 participants were included in the study (mean age, 57.61 ± 11.40 years; 51.78% were women). The mean score of HEI-2015 was 56.09 ± 13.40 (41.33 ± 6.28, 59.44 ± 5.54, and 76.90 ± 5.37 for inadequate, average, and optimal groups, respectively). After adjusting for covariates, higher HEI-2015 was associated with decreased AAC score (AAC-24: β = −0.121, 95% CI: −0.214, −0.028, P = 0.010; AAC-8: β= −0.054, 95% CI: −0.088, −0.019, P = 0.003) and lower risk of AAC (OR = 0.921, 95% CI: 0.855, 0.993, P = 0.031). Among the components of HEI-2015, a higher intake of fruits, greens, and beans was associated with a lower AAC score. Subgroup analysis showed that an inverse association of HEI-2015 with AAC score existed among different groups.ConclusionThe study presented that higher HEI-2015 was related to a lower AAC score and decreased risk of having AAC, indicating that greater compliance with 2015–2020 DGA, assessed by HEI-2015, might be beneficial for preventing vascular calcification and CVD among US adults.

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Greater Dietary Inflammatory Potential Is Associated With Higher Likelihood of Abdominal Aortic Calcification

Cited by 14 publications

References 69 publications

Association of Dietary Inflammatory Index (DII) and Depressive Disorders

Association of Dietary Inflammatory Index (DII) and Depressive Disorders

Beneficial effect of the short-chain fatty acid propionate on vascular calcification through intestinal microbiota remodelling

Association between healthy eating index-2015 and abdominal aortic calcification among US Adults

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