Gravity dependence of waves in the retinal spreading depression and in gel type Belousov–Zhabotinsky systems

Wiedemann, Meike; Lima, Vera Maura Fernandes de; Hanke, Wolfgang

doi:10.1039/b109166m

Cited by 21 publications

(18 citation statements)

References 11 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This might be a consequence of changed ion channel behaviour in the cellular membranes, as has been found in other experiments (Wiedemann et al 2003). A similar behaviour has been found with propagating waves in other excitable media, for example the special Belousov-Zhabotinsky reaction (Wiedemann et al 2002), or with propagating action potentials (Meissner & Hanke 2005). Additionally, our experiments have shown that the excitability of neuronal tissue itself is affected by gravity.…”

Section: Discussionsupporting

confidence: 88%

See 1 more Smart Citation

Central nervous tissue: an excitable medium. A study using the retinal spreading depression as a tool

Hanke

Lima

2007

Phil. Trans. R. Soc. A.

Self Cite

View full text Add to dashboard Cite

According to its physicochemical properties, neuronal tissue, including the central nervous system (CNS) and thus the human brain, is an excitable medium, which consequently exhibits, among other things, self-organization, pattern formation and propagating waves. Furthermore, such systems can be controlled by weak external forces. The spreading depression (SD), a propagating wave of excitation-depression, is such an event, which is additionally linked to a variety of medically important situations, classical migraine being just one example. Especially in retinal tissue, a true part of the CNS, the SD can be observed very easily with the naked eye and by video imaging techniques due to its big intrinsic optical signal.We have investigated the retinal SD and its control by external physical parameters such as gravity and temperature. Beyond this, especially due to its medical relevance, the control of CNS excitability by pharmacological tools is of specific interest, and we have studied this question in detail using the retinal SD as an experimental tool to collect information about the control of CNS tissue excitability.

show abstract

Section: Discussionsupporting

confidence: 88%

“…In studies investigating the influence of gravity on the oscillating chemical Belousov-Zhabotinsky reaction (Belousov 1959;Zaitkin & Zhabotinsky 1970), which, in a variety of parameters and in the theoretical framework used to describe it mathematically, is very similar to the SD, comparable results were found (Wiedemann et al 2002).…”

Section: Resultsmentioning

confidence: 84%

Central nervous tissue: an excitable medium. A study using the retinal spreading depression as a tool

Hanke

Lima

2007

Phil. Trans. R. Soc. A.

Self Cite

View full text Add to dashboard Cite

show abstract

“…According to Vladimir Zykov, the brusselator and the FitzHugh-Nagumo equations show mathematical identity. This mathematical identity of their dynamics, we thought, explained the parallel behavior of the two systems' responses to manipulations of weak external forces (gravity and electromagnetic forces, see Hanke et al [29] and Wiedemann et al [75]). …”

Section: The Basement Membrane and Extracellular Matrix Are Both Excimentioning

confidence: 82%

Extracellular matrix and its role in conveying glial/neural interactions in health and disease

Lima

Hanke

2017

JIN

Self Cite

View full text Add to dashboard Cite

Abstract. We review the concepts and findings that may be related to the occurrence of non-linear glial/neural dynamics involving interactions between polyelectrolytes of the extracellular matrix and the basement membranes that cover the endfeet of glia at CNS interfaces. Distortions of perception and blocking of learning expressed in functional syndromes are interpreted as macroscopic electrochemical patterns that emerge in grey matter through glial/neural interactions.

show abstract

“…Aus Experimenten mit anderen Systemen, die theoretisch gewisse Ähnlichkeiten mit AP aufweisen (retinale ᮣ Spreading Depression [2] und ᮣ Belousov-Zahbotinsky-Reaktion [7] …”

Section: S C H W E R K R a F T I I | Seminar Für Schülerunclassified

Hoch hinaus: Schüler forschen unter Weltraumbedingungen II

Meissner

Schwertner

Hanke

2003

Biologie in unserer Zeit

Self Cite

View full text Add to dashboard Cite

Gravity dependence of waves in the retinal spreading depression and in gel type Belousov–Zhabotinsky systems

Cited by 21 publications

References 11 publications

Central nervous tissue: an excitable medium. A study using the retinal spreading depression as a tool

Central nervous tissue: an excitable medium. A study using the retinal spreading depression as a tool

Extracellular matrix and its role in conveying glial/neural interactions in health and disease

Hoch hinaus: Schüler forschen unter Weltraumbedingungen II

Contact Info

Product

Resources

About