Graves’ disease and systemic lupus erythematosus: a Mendelian randomization study
Wei Xian,
Boyuan Liu,
Jinjian Li
et al.
Abstract:IntroductionPrevious observational studies have established a correlation between Graves’ disease(GD) and systemic lupus erythematosus(SLE). However, whether a causal relationship exists between these two diseases remains unknown.We utilized Mendelian randomization to infer the causal association between GD and SLE.MethodsThis study employed GWAS summary statistics of GD and SLE in individuals of Asian descent. The random effect inverse variance weighted (IVW) method was utilized to aggregate the causal effect… Show more
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