Grating-Based X-ray Phase Imaging Using Multiline X-ray Source

Abstract

Differential phase-contrast X-ray imaging has been performed in a Talbot-Lau configuration, where a multiline X-ray source was used instead of a combination of a hard-X-ray multiple slit and a normal focus X-ray generator. When the multiple slit is used, a high aspect ratio structure is needed and slit width should be below 10 mm for its function. The fabrication and use of such a multislit can be omitted using the presented configuration. The multiline X-ray source was developed by making grooves on a tungsten rotating anode, which was irradiated by an electron beam to generate X-rays. An array of 10 mm line sources with a pitch of 30 mm was formed and combined with a 4.5 mm pitch phase grating and a 5.3 mm pitch amplitude grating to generate differential phase contrast. With a total exposure time of 40 s, a differential phase image depicting cartilages was obtained.

Phase Contrast Imaging with Coded Apertures Using Laboratory-Based X-ray Sources

“…A third grating placed after the x-ray source must be employed in the laboratory version of the technique to create an array of individually coherent sources. An alternative method to obtain individual coherent sources is to cut grooves in the anode target of the x-ray source [10].…”

Diffraction Enhanced Phase Contrast Imaging of a Kitten Deciduous Tooth using Coherent X-ray Source

“…The development of phase contrast imaging relevant to medical application became active worldwide, among those are the Tsukuba PF -KEK and Harima Spring 8 as leading brands. Because of this kind of large-scale facility, it was recommended to utilize a large number of research developments in industry and government studies [34][35][36][37][38] . However, in order to utilize phase contrast imaging, coherent illumination is necessary.…”

“…In relation to this, LEBRA is a relatively small-sized linear accelerator driven x-ray source which is originally coherent monochromatic x-ray where phase contrast imaging can be easily done. Applying this principle, the possibility of compact facilityand clinical application is shown 38) . Presently, we repeat the actual proof of the experiment using internal organs with soft tissues for the advancement of clinical diagnosis.…”

Fundamental relationship between the noise properties of grating-based differential phase contrast CT and absorption CT: Theoretical framework using a cascaded system model and experimental validation

“…Both rotating-anode x-ray tubes and indirect-detection flat panel detectors (FPD) have been used in DPC-CT systems. 4,7,15,58 Incident photons are diffracted by the Talbot-Lau interferometer before interacting with the detector, as shown in Fig. 1.…”