The homotopy type of spaces of locally convex curves with fixed endpoints in Spin n+1 , the universal covering the orthogonal group SO n+1 for n ≥ 2, has been determined for n = 2 but is in general not known. The results in this paper have as one important aim trying to make progress in this problem. In the process, we prove a related conjecture of B. Shapiro and M. Shapiro regarding the behavior of fundamental systems of solutions to linear ordinary differential equations. We define the itinerary of a locally convex curve Γ : [0, 1] → Spin n+1 as a (finite) word w in the alphabet S n+1 {e} of non-trivial permutations. This word encodes the succession of non-open Bruhat cells of Spin n+1 pierced by Γ(t) as t ranges from 0 to 1. We prove that, for each word w, the subspace of curves of itinerary w is an embedded contractible (globally collared topological) submanifold of finite codimension, thus defining a stratification of the space of curves. We show how to obtain explicit (topologically) transversal sections for each of these submanifolds. We also study the neighboring relation between strata. This is an important step in the construction of abstract cell complexes mapped into the original space of curves by weak homotopy equivalences, which we cover in a follow-up paper.