Grass-mediated biogenic synthesis of silver nanoparticles and their drug delivery evaluation: A biocompatible anti-cancer therapy

Gul, Anam Rana; Shaheen, Farhat; Rafique, Rafia; Bal, Jyotiranjan; Waseem, Shahid; Park, Tae Jung

doi:10.1016/j.cej.2020.127202

Cited by 76 publications

(30 citation statements)

References 93 publications

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“…In addition, because silver (Ag) has a strong x-ray attenuation compared to iodinated agents used in imaging, there is significant interest in using AgNPs for x-ray computed tomography imaging and other optical imaging applications [26][27][28][29][30][31]. There is also interest in using them as drug delivery agents for cancer therapy [32][33][34] or rheumatoid arthritis therapy [35]. Consequently, it is expected that the increased production and use will lead to a significant accumulation of AgNPs in wastewater and the environment, potentially increasing exposure to humans [36][37][38].…”

Section: Introductionmentioning

confidence: 99%

Silver Nanoparticles Stable to Oxidation and Silver Ion Release Show Size-Dependent Toxicity In Vivo

et al. 2021

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Silver nanoparticles (AgNPs) are widely used in commerce, however, the effect of their physicochemical properties on toxicity remains debatable because of the confounding presence of Ag+ ions. Thus, we designed a series of AgNPs that are stable to surface oxidation and Ag+ ion release. AgNPs were coated with a hybrid lipid membrane comprised of L-phosphatidylcholine (PC), sodium oleate (SOA), and a stoichiometric amount of hexanethiol (HT) to produce oxidant-resistant AgNPs, Ag–SOA–PC–HT. The stability of 7-month aged, 20–100 nm Ag–SOA–PC–HT NPs were assessed using UV–Vis, dynamic light scattering (DLS), and inductively coupled plasma mass spectrometry (ICP-MS), while the toxicity of the nanomaterials was assessed using a well-established, 5-day embryonic zebrafish assay at concentrations ranging from 0–12 mg/L. There was no change in the size of the AgNPs from freshly made samples or 7-month aged samples and minimal Ag+ ion release (<0.2%) in fishwater (FW) up to seven days. Toxicity studies revealed AgNP size- and concentration-dependent effects. Increased mortality and sublethal morphological abnormalities were observed at higher concentrations with smaller nanoparticle sizes. This study, for the first time, determined the effect of AgNP size on toxicity in the absence of Ag+ ions as a confounding variable.

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Section: Introductionmentioning

confidence: 99%

Silver Nanoparticles Stable to Oxidation and Silver Ion Release Show Size-Dependent Toxicity In Vivo

et al. 2021

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“…And also due to their biocompatibility, drug delivery efficiency was improved significantly, which resulted in the promotion of elimination of cancer cells. [129]…”

Section: Antibacterial Activitymentioning

confidence: 99%

Bio‐mediated synthesis – A sustainable strategy for nanomaterials preparation: A comprehensive bibliometric review

et al. 2021

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Nanomaterials have been widely used in multi-aspect because of their particular physicochemical properties. However, traditional physical and chemical synthetic methods of nanomaterials are costly, they are easy to produce toxic by-products which are harmful to environment and human health. In recent years, the synthesis of nanomaterials via biological mediated method has shown great potential with the advantage of environmentally friendly, cost-effective and high-efficiency. Plants, microorganisms, and biological extracts are all excellent candidates for biosynthesis. Furthermore, these kinds of bio-genic materials have been applied in many fields such as environment remediation, catalytic reaction, anti-microbsis and anti-tumor. Thus, in order to grasp the research progress and development trend of nanomaterials synthesized by bio-mediated methods, a comprehensive overview is presented based on Web of Science database and bibliometric analysis. The results proved that the number of publications increased year by year from 2010 to 2020, India and China were the main two contributors. Some research institutions and researchers have formed their stable cooperative groups. Keywords analysis showed that the co-occurrence network could be divided into four clusters, "green synthesis," "AgNPs," "AuNPs," "nanoparticles," and "leaf extract" were the most popular words. Moreover, publishing journals, highly cited articles and major disciplines were also studied. The review will provide valuable references for future research.

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“…The use of other bio-based materials such as amino acids, bacterial isolates, fungus isolates and natural biopolymers, for other metal nanoparticles synthesis, all fall within the ambit of the “green synthesis.” 12–18 The exceptional properties of AgNPs made it an efficient resource with applications already extended into diverse human fields of endeavors, ranging from; potent antimicrobial agents, 19 constituents of food packaging materials, 20 as components of medical sutures coatings, 21 in analytical detection of diverse analytes 22 , 23 and as a delivery agent of some drugs, in conjunction with its role in cancer therapeutics. 24 …”

Section: Introductionmentioning

confidence: 99%

Multifarious Biological Applications and Toxic Hg2+ Sensing Potentiality of Biogenic Silver Nanoparticles Based on Securidaca inappendiculata Hassk Stem Extract

Jayeoye¹,

Eze²,

Olatunde³

et al. 2021

IJN

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Grass-mediated biogenic synthesis of silver nanoparticles and their drug delivery evaluation: A biocompatible anti-cancer therapy

Cited by 76 publications

References 93 publications

Silver Nanoparticles Stable to Oxidation and Silver Ion Release Show Size-Dependent Toxicity In Vivo

Silver Nanoparticles Stable to Oxidation and Silver Ion Release Show Size-Dependent Toxicity In Vivo

Bio‐mediated synthesis – A sustainable strategy for nanomaterials preparation: A comprehensive bibliometric review

Multifarious Biological Applications and Toxic Hg2+ Sensing Potentiality of Biogenic Silver Nanoparticles Based on Securidaca inappendiculata Hassk Stem Extract

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