Graphene/polyaniline electrodeposited needle trap device for the determination of volatile organic compounds in human exhaled breath vapor and A549 cell

Abstract

In this work, a graphene/polyaniline (G/PANI) electrodeposited coating was introduced as a novel extraction phase of needle trap microextraction (NTME) for the extraction of volatile organic compounds (VOCs).

A novel lung alveolar cell model for exploring volatile biomarkers of particle-induced lung injury

“…VOCs found in cell lines are advantageous for understanding the mechanism of VOC generation in patients. Additionally, using an in vitro study can prevent interference from exogenous contaminations, such as ambient air, food, and smoking 19 . The current method was suggested by Chen et al to discover volatile metabolites of lung cancer that have complex mechanisms in humans 20 , and several studies have investigated the release of VOCs from human cancer cells in vitro 21 , 22 .…”

Novel solid‐phase microextraction fiber coatings: A review

“…On top of that, graphene can also be used in the SPME fibers thanks to its nature of forming π-π interactions with a number of organic compounds. Until now, SPME fibers based on graphene have been triumphantly determined polycyclic aromatic hydrocarbons (PAHs) [51], BTEX isomers, volatile organic compounds that existed in the exhaled vapor of humans and cells [52]. A highlight must be mentioned that graphene was utilized to improve the specific surface area, embedded in the form of adsorbent, which could extract phenoxyacetic acid herbicides much more effectively [53].…”

Polydopamine coated hypodermic needles as a microextraction device for the determination of tricyclic antidepressants in oral fluid by direct infusion MS/MS

“…In-needle microextraction techniques consist of the connement of the sorbent inside a metallic needle. The sorbent can be coated as a thin lm on the inner surface of the needle [18][19][20] or packed (as particles or monolith) inside it. [21][22][23] In both cases, the technique allows the sample to ow through the needle boosting the interaction with the target analytes.…”

“…The miniaturized size of the needles requires little solvent for the elution, even when high sample volumes are processed, which is particularly interesting for an efficient preconcentration. In-needle microextraction, oen named as needle trap, has been extensively used in biological, 20,[24][25][26] food, 27,28 and environmental analysis. 29 The technique is commonly combined with a previous headspace extraction, as a clean-up step, when complex samples are processed.…”