Graphene-Palladium Composite for the Simultaneous Electrochemical Determination of Epinephrine, Ascorbic acid and Uric Acid

Renjini, S; Abraham, Pinky; Aparna, S.; Kumary, V. Anitha

doi:10.1149/2.0941914jes

Cited by 16 publications

(1 citation statement)

References 71 publications

(71 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A broad linear range was found between 10-11,460 µ M, with a LOD of 8 µ M. Results demonstrate that this nanocomposite is a suitable candidate for rapid, reproducible, and selective detection of AA in clinical samples. Abraham et al [210] developed a rGO/Pd-modified GCE to determine Epinephrine, AA, and uric acid, biomolecules that co-exist in the extracellular fluid of the central nervous system and serum. In this case, GO was synthesized via improved Hummer's method and subsequently subjected to solar exfoliation by exposure to solar rays, which resulted in the formation of rGO.…”

Section: Ascorbic Acidmentioning

confidence: 99%

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

Sainz-Urruela

Vera

Andrés

et al. 2021

IJMS

View full text Add to dashboard Cite

Over the last years, different nanomaterials have been investigated to design highly selective and sensitive sensors, reaching nano/picomolar concentrations of biomolecules, which is crucial for medical sciences and the healthcare industry in order to assess physiological and metabolic parameters. The discovery of graphene (G) has unexpectedly impulsed research on developing cost-effective electrode materials owed to its unique physical and chemical properties, including high specific surface area, elevated carrier mobility, exceptional electrical and thermal conductivity, strong stiffness and strength combined with flexibility and optical transparency. G and its derivatives, including graphene oxide (GO) and reduced graphene oxide (rGO), are becoming an important class of nanomaterials in the area of optical and electrochemical sensors. The presence of oxygenated functional groups makes GO nanosheets amphiphilic, facilitating chemical functionalization. G-based nanomaterials can be easily combined with different types of inorganic nanoparticles, including metals and metal oxides, quantum dots, organic polymers, and biomolecules, to yield a wide range of nanocomposites with enhanced sensitivity for sensor applications. This review provides an overview of recent research on G-based nanocomposites for the detection of bioactive compounds, providing insights on the unique advantages offered by G and its derivatives. Their synthesis process, functionalization routes, and main properties are summarized, and the main challenges are also discussed. The antioxidants selected for this review are melatonin, gallic acid, tannic acid, resveratrol, oleuropein, hydroxytyrosol, tocopherol, ascorbic acid, and curcumin. They were chosen owed to their beneficial properties for human health, including antibiotic, antiviral, cardiovascular protector, anticancer, anti-inflammatory, cytoprotective, neuroprotective, antiageing, antidegenerative, and antiallergic capacity. The sensitivity and selectivity of G-based electrochemical and fluorescent sensors are also examined. Finally, the future outlook for the development of G-based sensors for this type of biocompounds is outlined.

show abstract

Section: Ascorbic Acidmentioning

confidence: 99%

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

Sainz-Urruela

Vera

Andrés

et al. 2021

IJMS

View full text Add to dashboard Cite

show abstract

Hollow Reticular Shaped Highly Ordered Rice Husk Carbon for the Simultaneous Determination of Dopamine and Uric Acid

et al. 2020

View full text Add to dashboard Cite

We have prepared activated porous carbon material through simple pyrolysis method from rice husks (rhAC) for sensitive detection of dopamine (DA) and uric acid (UA). The prepared rhAC material was thoroughly characterized using various spectroscopic, microscopic, and electroanalytical techniques. Analysis of the voltammetric data showed that the analytes followed a first order reaction kinetics while following a 2e−/2H+ transfer process. We have discussed the possible oxidation mechanism for the analytes based on the results from our experimental analysis. The rhAC_GCE sensor was tested for interference, reproducibility, and stability. The sensor was also tested to evaluate its applicability in real life.

show abstract