Graphene Oxide Thin Films with Drug Delivery Function

Oliveira, Alexandra M. L.; Machado, Mónica; Silva, Gabriela A.; Bitoque, Diogo B.; Ferreira, Joana; Pinto, Luís Abegão; Ferreira, Quirina

doi:10.3390/nano12071149

Cited by 35 publications

(17 citation statements)

References 141 publications

(203 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, CNT lacks biodegradability and has a certain toxicity, even though it has many excellent properties [ 99 ]. In contrast, GO does not only have the advantage of negligible toxicity, but also provides feedback on drug loading and release due to its optical properties [ 100 , 101 ].…”

Section: Applications Of Go Gqds and Goqds Luminescencementioning

confidence: 99%

Photoluminescence and Fluorescence Quenching of Graphene Oxide: A Review

Xiao

Zhou

et al. 2022

Nanomaterials

View full text Add to dashboard Cite

In recent decades, photoluminescence (PL) material with excellent optical properties has been a hot topic. Graphene oxide (GO) is an excellent candidate for PL material because of its unique optical properties, compared to pure graphene. The existence of an internal band gap in GO can enrich its optical properties significantly. Therefore, GO has been widely applied in many fields such as material science, biomedicine, anti-counterfeiting, and so on. Over the past decade, GO and quantum dots (GOQDs) have attracted the attention of many researchers as luminescence materials, but their luminescence mechanism is still ambiguous, although some theoretical results have been achieved. In addition, GO and GOQDs have fluorescence quenching properties, which can be used in medical imaging and biosensors. In this review, we outline the recent work on the photoluminescence phenomena and quenching process of GO and GOQDs. First, the PL mechanisms of GO are discussed in depth. Second, the fluorescence quenching mechanism and regulation of GO are introduced. Following that, the applications of PL and fluorescence quenching of GO–including biomedicine, electronic devices, material imaging–are addressed. Finally, future development of PL and fluorescence quenching of GO is proposed, and the challenges exploring the optical properties of GO are summarized.

show abstract

Section: Applications Of Go Gqds and Goqds Luminescencementioning

confidence: 99%

Photoluminescence and Fluorescence Quenching of Graphene Oxide: A Review

Xiao

Zhou

et al. 2022

Nanomaterials

View full text Add to dashboard Cite

show abstract

“…The outstanding properties of this 2D material have led to many application proposals. To cite just a few of them: nanocomposites for bone tissue engineering [3], composites for multifunctional applications [4], lubrication [5,6], solar cells [7], ultracapacitors [8,9], batteries [10], sensors [11], catalysis [12], nanomedicine [13], fuel cells [14,15] or even energy harvesting [16].…”

Section: Introductionmentioning

confidence: 99%

Quantum Revivals in Curved Graphene Nanoflakes

2022

View full text Add to dashboard Cite

Graphene nanostructures have attracted a lot of attention in recent years due to their unconventional properties. We have employed Density Functional Theory to study the mechanical and electronic properties of curved graphene nanoflakes. We explore hexagonal flakes relaxed with different boundary conditions: (i) all atoms on a perfect spherical sector, (ii) only border atoms forced to be on the spherical sector, and (iii) only vertex atoms forced to be on the spherical sector. For each case, we have analysed the behaviour of curvature energy and of quantum regeneration times (classical and revival) as the spherical sector radius changes. Revival time presents in one case a divergence usually associated with a phase transition, probably caused by the pseudomagnetic field created by the curvature. This could be the first case of a phase transition in graphene nanostructures without the presence of external electric or magnetic fields.

show abstract

“…These pivotal characteristics allow it to interact with drugs through non-covalent interactions such as π-π interaction. As a derivative of graphene, GO is also a promising drug delivery vehicle [ 4 ]. Apart from features similar to pristine graphene, abundant hydroxyl, epoxy, and carboxyl functional groups in GO enable it to have a higher adsorption capacity for drug molecules than pristine graphene [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Theoretical Study on the Aggregation and Adsorption Behaviors of Anticancer Drug Molecules on Graphene/Graphene Oxide Surface

Gong

Zhou

et al. 2022

Molecules

View full text Add to dashboard Cite

Graphene and its derivatives are frequently used in cancer therapy, and there has been widespread interest in improving the therapeutic efficiency of targeted drugs. In this paper, the geometrical structure and electronic effects of anastrozole(Anas), camptothecin(CPT), gefitinib (Gefi), and resveratrol (Res) on graphene and graphene oxide(GO) were investigated by density functional theory (DFT) calculations and molecular dynamics (MD) simulation. Meanwhile, we explored and compared the adsorption process between graphene/GO and four drug molecules, as well as the adsorption sites between carriers and payloads. In addition, we calculated the interaction forces between four drug molecules and graphene. We believe that this work will contribute to deepening the understanding of the loading behaviors of anticancer drugs onto nanomaterials and their interaction.

show abstract

Graphene Oxide Thin Films with Drug Delivery Function

Cited by 35 publications

References 141 publications

Photoluminescence and Fluorescence Quenching of Graphene Oxide: A Review

Photoluminescence and Fluorescence Quenching of Graphene Oxide: A Review

Quantum Revivals in Curved Graphene Nanoflakes

Theoretical Study on the Aggregation and Adsorption Behaviors of Anticancer Drug Molecules on Graphene/Graphene Oxide Surface

Contact Info

Product

Resources

About