Graphene oxide-gold nanozyme for highly sensitive electrochemical detection of hydrogen peroxide

Nanozyme-based electrochemical biosensors for disease biomarker detection

“…Among the oxidoreductase nanozymes, peroxidase-and oxidase-mimicking nanomaterials are mostly explored for electrochemical biosensors (Table 1). The common nanomaterials with peroxidase mimetics includes metal nanoparticles (AuNPs, 50 PdNPs 51 ), metal oxides (Fe2O3, 52,53 Au-NPFe2O3NC, 54,55 Fe3O4 MNP, 56 CeO2/NiO, 57 and CuO 58 ), core-shell nanostructure(Au@Pt 59 ), dendrite (dealloyed-AuNi@pTBA, 60 Cu-Co alloy dendrite 61 ), carbonbased composite(GO-AuNP, 62 His@AuNCs/rGO, 63 PtNPs decorated CNT 64 ), and metal-organic frameworks (MOFs). Unlike other nanomaterials, MOFs have drawn enormous interest as a new class of nanozymes due to their uniform cavities which are likely to provide biomimetic active centers and enzyme-like pseudo-substrate-binding pockets.…”

Biomimetic graphene oxide-cationic multi-shaped gold nanoparticle-hemin hybrid nanozyme: Tuning enhanced catalytic activity for the rapid colorimetric apta-biosensing of amphetamine-type stimulants

“…epoxy, carbonyl, carboxyl and hydroxyl) [25]. Despite the peroxidase mimic activity of AuNPs and graphene, their catalytic efficiency in sensor technology can be enhanced further by forming hybrid nanostructures [26,27]. Additionally, the incorporation of hemin (iron protoporphyrin IX) in a peroxidase mimic assay can also aid catalytic enhancement of the sensor.…”

Palladium Nanoclusters Uniformly Enveloped Electrochemically Activated Graphene for Highly Sensitive Hydrogen Peroxide Sensor

“…Recently, Gr composite metals nanoparticles could be suggested as potential candidates because of its abundant of oxygen groups that promote the electron transfer process between target analyte and electrode surface. Thus, metals nanoparticles doped Gr have been applied in order to increase the electrocatalytic activity of H 2 O 2 sensors, such as Pt, Au, ZnO, CoO, MnO 2 . Among of them, platinum nanoparticles (PdNPs) were used for designing different H 2 O 2 sensors due to its interesting properties, such as high conductivity and electrocatalytic activity that enhance the electron transfer process of H 2 O 2 as well as reduce the reduction overpotential .…”