Graphene oxide-based nanomaterials for electrochemical bio/immune sensing and its advancements in health care applications: A review

Devi, K.S. Shalini; Prakash, Jai; Tsujimura, Seiya

doi:10.1016/j.hybadv.2023.100123

Cited by 6 publications

(5 citation statements)

References 114 publications

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“…Graphene-based biosensors possess exceptional specificity and selectivity, rendering them invaluable instruments for the prompt detection of diseases. Moreover, the incorporation of graphene with various transduction techniques improves the efficiency of biosensors, hence facilitating the advancement of sophisticated diagnostic instruments [ 66 , 67 ].…”

Section: Important Theranostic Features Of Nanoparticlesmentioning

confidence: 99%

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Theranostics: a multifaceted approach utilizing nano-biomaterials

Yasir,

Mishra,

Tripathi

et al. 2024

Discover Nano

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Biomaterials play a vital role in targeting therapeutics. Over the years, several biomaterials have gained wide attention in the treatment and diagnosis of diseases. Scientists are trying to make more personalized treatments for different diseases, as well as discovering novel single agents that can be used for prognosis, medication administration, and keeping track of how a treatment works. Theranostics based on nano-biomaterials have higher sensitivity and specificity for disease management than conventional techniques. This review provides a concise overview of various biomaterials, including carbon-based materials like fullerenes, graphene, carbon nanotubes (CNTs), and carbon nanofibers, and their involvement in theranostics of different diseases. In addition, the involvement of imaging techniques for theranostics applications was overviewed. Theranostics is an emerging strategy that has great potential for enhancing the accuracy and efficacy of medicinal interventions. Despite the presence of obstacles such as disease heterogeneity, toxicity, reproducibility, uniformity, upscaling production, and regulatory hurdles, the field of medical research and development has great promise due to its ability to provide patients with personalised care, facilitate early identification, and enable focused treatment.

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Section: Important Theranostic Features Of Nanoparticlesmentioning

confidence: 99%

“…Recently, C dots were employed to identify tumour cells in order to investigate early bone metastases [ 6 ]. QD is also used to identify the H 1 N 1 and H 3 N 2 subtypes of the influenza A virus and to diagnose hepatitis B virus (HBV) [ 67 , 68 ].…”

Section: Important Theranostic Features Of Nanoparticlesmentioning

confidence: 99%

Theranostics: a multifaceted approach utilizing nano-biomaterials

Yasir,

Mishra,

Tripathi

et al. 2024

Discover Nano

View full text Add to dashboard Cite

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“…When creating impedimetric immunosensors, it is important to prevent possible nonspecific binding of the analyte to nontarget components, which introduces a spurious signal into the impedance measurements. For this purpose, free spaces on the surface of the chip that were not functionalized with antibodies are blocked with BSA [204], casein [205], twin-surfactants [206], commercial solutions such as SmartBlock™ [207], and other compounds.…”

Section: Impedimetric Detection Of Proteins Using Antibodiesmentioning

confidence: 99%

Hybrid Impedimetric Biosensors for Express Protein Markers Detection

Sitkov,

Ryabko,

Moshnikov

et al. 2024

Micromachines

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Impedimetric biosensors represent a powerful and promising tool for studying and monitoring biological processes associated with proteins and can contribute to the development of new approaches in the diagnosis and treatment of diseases. The basic principles, analytical methods, and applications of hybrid impedimetric biosensors for express protein detection in biological fluids are described. The advantages of this type of biosensors, such as simplicity and speed of operation, sensitivity and selectivity of analysis, cost-effectiveness, and an ability to be integrated into hybrid microfluidic systems, are demonstrated. Current challenges and development prospects in this area are analyzed. They include (a) the selection of materials for electrodes and formation of nanostructures on their surface; (b) the development of efficient methods for biorecognition elements’ deposition on the electrodes’ surface, providing the specificity and sensitivity of biosensing; (c) the reducing of nonspecific binding and interference, which could affect specificity; (d) adapting biosensors to real samples and conditions of operation; (e) expanding the range of detected proteins; and, finally, (f) the development of biosensor integration into large microanalytical system technologies. This review could be useful for researchers working in the field of impedimetric biosensors for protein detection, as well as for those interested in the application of this type of biosensor in biomedical diagnostics.

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“…8,19–21 More specifically, ZNSs have been extensively investigated in biomedical applications due to their biocompatibility and ease of tailoring their optical, electrical, structural, and morphological properties. 22–24…”

Section: Introductionmentioning

confidence: 99%